Results 21 to 30 of about 32,562 (264)
PUF3 RNA binding protein of Trypanosoma cruzi regulates mitochondrial morphology and function
The RNA-binding PUF proteins are post-transcriptional regulators found throughout the eukaryotic domain. In Trypanosoma cruzi, ten Puf genes termed Puf1 to Puf10 have been identified.
Ana María Mejía-Jaramillo +6 more
doaj +1 more source
Vacuna contra el virus de Papiloma Humano: Resultados a un año de su incorporación al calendario de vacunación [PDF]
En el abordaje integral del control y prevención del cáncer cérvico uterino, la incorporación de la vacuna contra el virus papiloma humano es una importante oportunidad para reducir de forma significativa la incidencia y mortalidad por esta enfermedad.
Nathalia, Katz +3 more
doaj
Introduction: Cutaneous leishmaniasis, caused by parasites of the genus Leishmania, is a disease with high incidence in Colombia. The diagnosis and identification of the infectious species are critical factors when selecting and initiating treatment ...
Johana Marin +5 more
doaj +1 more source
Macrophage‐derived MLKL in alcohol‐associated liver disease: Regulation of phagocytosis
EtOH causes leaky gut allowing bacteria and PAMPs into the liver, resulting in hepatic inflammation and injury. We demonstrate that LPS induces STAT1‐mediated expression and phosphorylation of MLKL in macrophages and identify a novel function that myeloid MLKL translocates to phagosomes and lysosomes and regulates phagocytosis, which contributes to the
Xiaoqin Wu +16 more
wiley +1 more source
Chagas disease is a neglected vector-borne zoonosis caused by the parasite Trypanosoma cruzi that is primarily transmitted by insects of the subfamily Triatominae.
Lídia Gual-Gonzalez +7 more
doaj +1 more source
Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird +9 more
wiley +1 more source
The NADPH oxidase NOX4 regulates redox and metabolic homeostasis preventing HCC progression
Loss of NOX4 in HCC tumor cells induces metabolic reprogramming in a Nrf2/MYC‐dependent manner to promote HCC progression. Abstract Background and Aims The NADPH oxidase NOX4 plays a tumor‐suppressor function in HCC. Silencing NOX4 confers higher proliferative and migratory capacity to HCC cells and increases their in vivo tumorigenic potential in ...
Irene Peñuelas‐Haro +14 more
wiley +1 more source
Principales resultados de la tercera Encuesta Nacional de Factores de Riesgo de enfermedades no transmisibles en Argentina [PDF]
La vigilancia de las enfermedades no transmisibles (ENT) y sus factores de riesgo es esencial para diseñar y evaluar políticas efectivas. En 2013 se realizó la tercera Encuesta Nacional de Factores de Riesgo de ENT (ENFR).
Mariana, Galante +10 more
doaj
Introduction: In cutaneous leishmaniasis, the host immune response is responsible for the development of skin injuries but also for resolution of the disease especially after antileishmanial therapy.
Andrés Montoya +6 more
doaj +1 more source
Objective We examined whether 18 months of strength training in individuals with knee varus alignment and medial tibiofemoral osteoarthritis (OA) reduced knee joint loads during walking compared to an attention control group. Methods This study was a secondary analysis of a randomized clinical trial that compared the effects of strength training to a ...
Stephen P. Messier +12 more
wiley +1 more source

