Corrigendum: RfpA, RfpB, and RfpC are the Master Control Elements of Far-Red Light Photoacclimation (FaRLiP). [PDF]
Zhao C, Gan F, Shen G, Bryant DA.
europepmc +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
A set of synthetic versatile genetic control elements for the efficient expression of genes in Actinobacteria. [PDF]
Horbal L, Siegl T, Luzhetskyy A.
europepmc +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
IDENTIFICATION OF PARAMETERS OF ELEMENTS PHASE CONTROL
The problem of identifying the parameters of the stochastic phase control system defined by mathematical models of the process and meter signals in the form of equations processes random structure. An example showing the performance of the identification
J. M. Said
doaj
RfpA, RfpB, and RfpC are the Master Control Elements of Far-Red Light Photoacclimation (FaRLiP). [PDF]
Zhao C, Gan F, Shen G, Bryant DA.
europepmc +1 more source
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Alternative splicing of TAF6: downstream transcriptome impacts and upstream RNA splice control elements. [PDF]
Kamtchueng C +6 more
europepmc +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Aromatic interactions as control elements in stereoselective organic reactions. [PDF]
Krenske EH, Houk KN.
europepmc +1 more source

