Results 11 to 20 of about 1,309,976 (267)

Comparison of the major cell populations among osteoarthritis, Kashin–Beck disease and healthy chondrocytes by single-cell RNA-seq analysis

open access: yesCell Death and Disease, 2021
Chondrocytes are the key target cells of the cartilage degeneration that occurs in Kashin–Beck disease (KBD) and osteoarthritis (OA). However, the heterogeneity of articular cartilage cell types present in KBD and OA patients and healthy controls is ...
Xi Wang   +10 more
doaj   +1 more source

Comparative analysis of the gut microbiota composition between knee osteoarthritis and Kashin-Beck disease in Northwest China

open access: yesArthritis Research & Therapy, 2022
Background Osteoarthritis (OA) and Kashin-Beck disease (KBD) both are two severe osteochondral disorders. In this study, we aimed to compare the gut microbiota structure between OA and KBD patients.
Yujie Ning   +15 more
doaj   +1 more source

The expression of the elements of the internal control system graphical representation

open access: yesBuhalterinės Apskaitos Teorija ir Praktika, 2014
The results of the analysis of scientific literature showed that scientists disagree and do not share the same opinion on the expression of the elements of the internal control system.
Lukas Giriūnas, Jonas Mackevičius
doaj   +1 more source

Assessment of Sustainable Elimination Criteria for Iodine Deficiency Disorders Recommended by International Organizations

open access: yesFrontiers in Nutrition, 2022
Enormous efforts have been made to evaluate the worldwide prevention and control of iodine deficiency disorders (IDDs). This study evaluated China's achievements in IDD prevention and control against WHO criteria for sustainable elimination of IDD.
Lijun Fan   +4 more
doaj   +1 more source

Genetic Variants and Protein Alterations of Selenium- and T-2 Toxin-Responsive Genes Are Associated With Chondrocytic Damage in Endemic Osteoarthropathy

open access: yesFrontiers in Genetics, 2022
The mechanism of environmental factors in Kashin–Beck disease (KBD) remains unknown. We aimed to identify single nucleotide polymorphisms (SNPs) and protein alterations of selenium- and T-2 toxin–responsive genes to provide new evidence of chondrocytic ...
Yujie Ning   +21 more
doaj   +1 more source

Multimorbidity status and risk factors among adults aged 45-64 years in 15 provinces of China in 2018: Based on association rule analysis

open access: yes环境与职业医学
BackgroundMultimorbidity imposes a heavy burden on individuals, families, and society. There are relatively few studies exploring patterns of multimorbidity among middle-aged adults in China.
Zhiru WANG   +7 more
doaj   +1 more source

Development of a Prototype of a Protective UV-C Half-Face Mask with Implementation of Additive Technology

open access: yesCommunications, 2023
The authors of this manuscript present development of a prototype protective UV-C half-face mask. The first stage of this study focuses on proposing a UV-C half-face mask design and the second phase investigates the quality of printings, 3D/2D roughness ...
Daniel Varecha   +8 more
doaj   +1 more source

Controlling Elements and the Gene

open access: yesCold Spring Harbor Symposia on Quantitative Biology, 1956
In a recent brief review (McClintock, 1956), a description was given of types of elements carried in the maize chromosomes that serve to control gene action and to induce, at the site of the gene, heritable modifications affecting this action. These elements were initially discovered because they do not remain at one position in the chromosome ...
openaire   +2 more sources

Detection of selenoprotein transcriptome in chondrocytes of patients with Kashin–Beck disease

open access: yesFrontiers in Cell and Developmental Biology, 2023
Background: Kashin–Beck disease (KBD) is a deformed osteochondral disease with a chronic progression that is restrictively distributed in eastern Siberia, North Korea, and some areas of China, and selenium deficiency has been identified as an important ...
Yi Gong   +17 more
doaj   +1 more source

Abnormal expression of TSG-6 disturbs extracellular matrix homeostasis in chondrocytes from endemic osteoarthritis

open access: yesFrontiers in Genetics, 2022
Background and aims: Kashin-Beck disease (KBD) is a unique endemic osteochondropathy with unclear pathogenesis in China. T-2 toxin exposure has been identified as a significant risk factor of KBD.
Yujie Ning   +16 more
doaj   +1 more source

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