Results 191 to 200 of about 1,309,976 (267)

Post-transcriptional regulation of mRNA stability in pancreatic ductal adenocarcinoma. [PDF]

open access: yesFront Immunol
Wang H   +8 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Predictive modeling of signal-responsive cis-elements in human red blood cell precursors. [PDF]

open access: yesNucleic Acids Res
Dogiparthi VR   +5 more
europepmc   +1 more source

Use and Public Reporting of Predetermined Change Control Plans for AI-Enabled Medical Devices.

open access: yesJAMA Health Forum
Dabek PA   +4 more
europepmc   +1 more source

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