Results 31 to 40 of about 4,537,045 (350)
The anglocentric tendency in the history of information engineering [PDF]
This paper examines the anglocentric nature of much writing on the history of technology, taking as an example important research results from the first half of the last century published in German and Russian in the field of information engineering. By ‘
Bissell, Christopher
core
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile +8 more
wiley +1 more source
Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley +1 more source
Control System Engineering Design in Three Phase Motor [PDF]
This study aimed to determine whether the computer can be used to control threephaseinduction motor with the help of Centronic interfaces and peripherals that runwith the program.These peripheral circuits consist of electronic components (circuit relay ...
Aqwam Rosadi Kardian, SKom, MM Aqwam Rosadi Kardian, SKom, MM +1 more
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Nicotinamide (NIC) and nicotinic acid (NIA) are proposed as stress signaling compounds in plants. Oxidative stress may lead to single strand breaks (SSB) in DNA, which activate poly(ADP‐ribose) polymerase (PARP). NIC and NIA are then formed from NAD. NIC and NIA can promote epigenetic changes leading to the expression of defense genes specific for the ...
Torkel Berglund, Anna B. Ohlsson
wiley +1 more source
Computer program for the design of toroidal transformers [PDF]
Program relieves designer of most of the computational details, while he maintains control over most engineering decisions. Number of specifications that must be supplied by user allows for considerable flexibility and for exercise of engineering ...
Dayton, J. A., Jr.
core +1 more source
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer +10 more
wiley +1 more source
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican +7 more
wiley +1 more source
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona +4 more
wiley +1 more source
Detailed and GlobalAnalysis of a Remedial Course's Impact on Incoming Students' Marks [PDF]
Engineering incoming students are facing great difficulties to overcome first course subjects. To tackle that situation and increase the students’ success a Remedial course in Mathematics was offered to Informatics Engineering freshmen.
Castiñeira Holgado, Elena +2 more
core +1 more source

