Results 101 to 110 of about 5,940,261 (349)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Nonlinear control systems, design methods [PDF]

, 1999
The sections in this article are: The Regulation Problem, Linear Time-Invariant Systems,Feedback Linearization, Passivity-Based Control, Control Under Model and Parameter Uncertainties, Third-Order Feedback Linearizable Systems, Conclusion ...
Webster, J.G., Loria, A., Nijmeijer, H.
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Critical damping characteristics of a SDOF system with fractional derivative of a wide range of order

Nihon Kikai Gakkai ronbunshu, 2018
In this study, vibration characteristics of a single-degree-of-freedom linear oscillator with the fractional order derivative are examined in terms of the critical damping over a wide range of the order of the fractional derivative by using numerical ...
Hideyuki KIMURA, Takahiro TSUCHIDA, Koji KIMURA   +2 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Identification for robust control of complex systems : algorithm and motion application [PDF]

, 2015
Increasing performance demands in control applications necessitate accurate modeling of complex systems for control. The aim of this chapter is to develop a new system identification algorithm that delivers models that are suitable for subsequent robust ...
Steinbuch, M., Oomen, T.A.E., Lovera, M.
core   +1 more source

A proposed plant classification framework for smart agricultural applications using UAV images and artificial intelligence techniques

Alexandria Engineering Journal
Utilizing Wireless Sensor Networks (WSNs), Internet of Things (IoTs) sensors, and Unmanned Aerial Vehicles (UAVs), in conjunction with optimization techniques and machine learning algorithms, can present a novel approach to Precision Agricultural (PA ...
Shymaa G. Eladl, Amira Y. Haikal, Mahmoud M. Saafan, Hanaa Y. ZainEldin   +3 more
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source