Results 101 to 110 of about 806,809 (312)

V-Model Role Engineering [PDF]

The paper focuses on role engineering which is an important topic in the development of access control system, particularly when considering Role Based Access Control – RBAC models.
Radu CONSTANTINESCU
core  

International Conference on Industry, Engineering, and Management Systems 2025

Published in SOAR: Shocker Open Access Repository by Wichita State University Libraries Technical Services, November 2025. 2025 IEMS Officers: Gamal Weheba (Conference Chair); Hesham Mahgoub (Program Chair); Dalia Mahgoub (Technical Director); Ed Sawan ...
International Conference on Industry, Engineering, and Management Systems
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

A conceptual system design and managerial complexity competency model [PDF]

, 2013
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Complex adaptive systems are usually difficult to design and control.
Amaechi, Austin Oguejiofor
core  

Discretisation method and stability criteria for non-linear systems under discrete-time time delay control

, 2011
Time delay control (TDC) for non-linear systems has rapidly drawn attention as a result of its unusually robust performance and yet its extraordinarily compact form. In many real applications, TDC has been implemented digitally and the time delay, λ, was
Stefanov, D., D. Stefanov, P.H. Chang, Jung, J. H., Chang, P. H., J.H. Jung   +5 more
core   +1 more source

NONLINEAR INTEGRAL CONTROL DESIGN FOR DC MOTOR SPEED CONTROL WITH UNKNOWN AND VARIABLE EXTERNAL TORQUE

Journal of Engineering and Sustainable Development, 2016
In this work, a nonlinear integral controller is proposed for a Direct Current (DC) motor model in the presence of a variable and unknown external load and for a constant and variable reference velocity. The nonlinear integral term is designed simply by
Shibly Ahmed Al-Samarraie, Bashar Fateh Midhat, Ivan Isho Gorial   +2 more
doaj  

DMARS_WGO: a deep reinforcement-driven hybrid metaheuristic for intelligent adaptive optimization

Scientific Reports
Metaheuristics optimization algorithms have established themselves as a new cornerstone in the area of complex, nonlinear, and high-dimensional problems of science and engineering.
Nada R. Yousif, Eman M. El-Gendy, Amira Y. Haikal   +2 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Architecting Joint Command and Control System of Systems Capability Certifications [PDF]

, 2007
Command, Control, Communications, Computers, and Intelligence (C4I) systems, each originally designed to address a single warfighting function, have been assembled into an interdependent C4I System of Systems (SoS).
Patel, Jaykant, Martin, Calvin, Medina, Jorge, Schoen, Tim, Willis, Ronald, Trinh, Khai, Hoesly, Scot, Medina, Vince, Huseth, Scott, Krider, Steven, Acosta, Jacob, Rangi, Kamaljit, Lamb, Jeremy, Nguyen, Michael   +13 more
core  

Supervisory control of multilevel discrete-event systems with a bus structure

, 2019
High-tech systems often contain a few components with many dependencies across the system, acting as system-level integrating components. In a hierarchical system decomposition, such so-called bus components tend to be placed in the top node.
van de Mortel - Fronczak, Asia, Reniers, Michel, Goorden, Martijn, Reniers, Michel; id_orcid, Fokkink, Wan, Dingemans, Calvin, Rooda, Koos, Goorden, Martijn; id_orcid   +7 more
core   +1 more source