Results 121 to 130 of about 806,809 (312)
Nonlinear control systems, design methods
, 1999 The sections in this article are: The Regulation Problem, Linear Time-Invariant Systems,Feedback Linearization, Passivity-Based Control, Control Under Model and Parameter Uncertainties, Third-Order Feedback Linearizable Systems, Conclusion ...
Webster, J.G., Loria, A., Nijmeijer, H.
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Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Command and control for distributed lethality [PDF]
, 2017 Exercising command and control (C2) during naval distributed lethality operations presents a complex system of systems (SOS) challenge in support of maritime control. Applying a model based systems engineering (MBSE) approach to C2 within the distributed
Kelly, Erik +7 more
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Control Engineering and Management Systems
Measurement + Control, 1969 V. A. J. Gifford DLC, CEng, MIProdE, FIWSP, MBIM
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Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Identification for robust control of complex systems : algorithm and motion application
, 2015 Increasing performance demands in control applications necessitate accurate modeling of complex systems for control. The aim of this chapter is to develop a new system identification algorithm that delivers models that are suitable for subsequent robust ...
Steinbuch, M., Oomen, T.A.E., Lovera, M.
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Control Engineering Approach to Management Systems
Measurement + Control, 1970 Sydney Paulden
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Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source