Results 121 to 130 of about 5,940,261 (349)

Design and Simulation of L1-Adaptive Controller for Position Control of DC Servomotor

Al-Khawarizmi Engineering Journal, 2017
This paper presents L1-adaptive controller for controlling uncertain parameters and time-varying unknown parameters to control the position of a DC servomotor.
Mohammed Ali S. Mohammed, Amjad J. Humaidi, Ammar A. Al jodah   +2 more
doaj  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

A conceptual system design and managerial complexity competency model [PDF]

, 2013
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Complex adaptive systems are usually difficult to design and control.
Amaechi, Austin Oguejiofor
core  

MSCADMpox: A novel multi-stage classification model for effective monkeypox classification

Complex & Intelligent Systems
Monkeypox (Mpox) is a skin disease that appeared after the COVID-19 pandemic and spread to 127 countries. Early diagnosis of Mpox according to symptoms is difficult because it is closer to measles and chickenpox symptoms, while both lesions are ...
Doaa Ahmed Arafa, Sarah M. Ayyad, Mohamed M. Abdelsalam   +2 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Architecting Joint Command and Control System of Systems Capability Certifications [PDF]

, 2007
Command, Control, Communications, Computers, and Intelligence (C4I) systems, each originally designed to address a single warfighting function, have been assembled into an interdependent C4I System of Systems (SoS).
Patel, Jaykant, Martin, Calvin, Medina, Jorge, Schoen, Tim, Willis, Ronald, Trinh, Khai, Hoesly, Scot, Medina, Vince, Huseth, Scott, Krider, Steven, Acosta, Jacob, Rangi, Kamaljit, Lamb, Jeremy, Nguyen, Michael   +13 more
core  

A new framework for mental illnesses diagnosis using wearable devices aided by improved convolutional neural network

Scientific Reports
Stress inherent in the modern world is considered one of the main causes of Mental Health Disorders (MHDs) that spread in every country around the world.
Hend S. Saad, John F. W. Zaki, Mohamed M. Abdelsalam   +2 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

NONLINEAR INTEGRAL CONTROL DESIGN FOR DC MOTOR SPEED CONTROL WITH UNKNOWN AND VARIABLE EXTERNAL TORQUE

Journal of Engineering and Sustainable Development, 2016
In this work, a nonlinear integral controller is proposed for a Direct Current (DC) motor model in the presence of a variable and unknown external load and for a constant and variable reference velocity. The nonlinear integral term is designed simply by
Shibly Ahmed Al-Samarraie, Bashar Fateh Midhat, Ivan Isho Gorial   +2 more
doaj  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source