Results 71 to 80 of about 806,809 (312)

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Advances in control engineering

open access: yes, 2015
The last twenty years have seen a radical step-change in the capability and application of Control Engineering, brought about by advances in computational speed and capacity.
Stewart, Paul
core   +1 more source

Design of Nonlinear PID and FOPID Controllers for Electronic Throttle Valve Plate’s Position

open access: yesJournal of Electrical and Computer Engineering
The electronic throttle valve (ETV) system is one of the essential parts of the automobile because it controls the amount of airflow into the engine’s combustion system. In fact, there are challenges in ETV control due to several nonsmooth nonlinearities,
Mohamed Jasim Mohamed   +1 more
doaj   +1 more source

An Innovative Damped Cuckoo Search Algorithm With a Comparative Study Against Other Adaptive Variants

open access: yesIEEE Access, 2019
This paper aims to find the best variant of Cuckoo Search Algorithm that makes the step size of Lévy flight adaptive. For this reason, we introduce a new variant of CSA called Damped Cuckoo Search (DCS) in which the step size of Lévy ...
Mohamed Reda   +3 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Control of Mechatronic Systems

open access: yes, 2017
This book introduces researchers and advanced students with a basic control systems background to an array of control techniques which they can easily implement and use to meet the required performance specifications for their mechatronic applications ...
Bilin Aksun-Güvenç   +7 more
core   +1 more source

Biological Systems Thinking for Control Engineering Design

open access: yesActa Polytechnica, 2004
Artificial neural networks and genetic algorithms are often quoted in discussions about the contribution of biological systems thinking to engineering design.
D. J. Murray-Smith
doaj  

Hand-like autonomous flying robot for airborne grasping and interaction

open access: yesNature Communications
Birds’ extraordinary aerial agility and environmental interaction enable complex tasks such as mid-air hunting, perching, and nest-building, inspiring the development of advanced aerial robots with similar manipulation capabilities.
Yuze Wu   +6 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Home - About - Disclaimer - Privacy