Results 61 to 70 of about 16,838,296 (301)

Annual Report on the Environment in Japan

, 2009
The white paper on comprehensive environmental policy describes the role of Japan's economy in a sound global environment. In the first part, the report describes current the environmental conditions of the Earth and of Japan, human activities in Japan ...
[Japan] Ministry of the Environment
core  

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

INTERNAL AUDIT EFFECTIVENESS AND ACCOUNTABILITY OF LOCAL GOVERNMENT ADMINISTRATION IN KWARA STATE

Gusau Journal of Accounting and Finance
Despite the constitutional proximity of local governments to grassroots populations, issues such as financial mismanagement, corruption, and poor service delivery remain prevalent, raising concerns about the efficacy of existing accountability ...
Abdulraheem Olayiwola KADIR, Ibrahim GARBA   +1 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Environmental radiation surveillance in Kansas, 1977 and 1978

, 1979
"Fall 1979." Prepared by Harold L. Spiker, Chief, Surveillance and Emergency Planning Section; Gerald A. Stoltenberg, Director, Division of Environment; Gerald W.
Kansas Bureau of Radiation Control
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Environmental radiation surveillance in Kansas, 1974

, 1975
"June 1975." Prepared by: David J. Larson, Chief, Surveillance Section; Melville W. Gray, Director, Division of Environment; Gerald W. Allen, Director, Bureau of Radiation ControlThe State of Kansas, Department of Health and Environment ...
Kansas Bureau of Radiation Control
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source