Results 91 to 100 of about 9,499 (219)

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Optimal control for systems governed by parabolic equations without initial conditions with controls in the coefficients

Electronic Journal of Differential Equations, 2017
We consider an optimal control problem for systems described by a Fourier problem for parabolic equations. We prove the existence of solutions, and obtain necessary conditions of the optimal control in the case of final observation when the control ...
Mykola Bokalo, Andrii Tsebenko
doaj  

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

System Identification Determination of Ship Maneuvering Hydrodynamic Coefficients Based on Free-running Model Test Results

نشریه مهندسی دریا, 2015
Ship maneuvering performance evaluation is essential for primary design stages. Ship maneuvering calculations, horizontal plane motion control and development of maneuvering simulators need a mathematical description of ship maneuvering.
Sajad Hajizadeh, Mohammad saeid seif, hamid Mehdigholi   +2 more
doaj  

Quality Control Charts for Multivariate EWMA Daubechies Discrete Wavelet Transformation Coefficients

المجلة العراقية للعلوم الاحصائية
Multivariate exponential weighted moving averages (MEWMA) are used to control several qualitative properties together of production processes. This article proposes the creation of new charts to control and monitor multivariate qualitative property ...
Marwan Tareq Hasan, Taha Hussein Ali, Nazeera Sedeek Kareem   +2 more
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Flow characteristics of control valve for different strokes

EPJ Web of Conferences, 2016
The article deals with the determination of flow characteristics and loss coefficients of control valve when the water flows in the interval of operating parameters, including the evaluation of vapour and air cavitation regime. The characteristics of the
Jablonská Jana, Kozubková Milada
doaj   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Real time dynamic adhesion coefficient estimation and BP neural network optimized lateral stability control for distributed drive electric vehicles

Scientific Reports
To address the instability issues of distributed-drive electric vehicles (DDEV) operating on roads with abrupt changes in adhesion coefficients, a lateral stability control strategy and torque distribution method based on backpropagation (BP) neural ...
Zhigang Zhou, Ruili Yang, Fang Xu, Wei Shen   +3 more
doaj   +1 more source