Results 161 to 170 of about 16,569,160 (252)

Breathing easier in Rhode Island : success stories from the Rhode Island Asthma Control Program

Rhode Island\u2019s Asthma Control Program and its partners focus on communities with the greatest needs. They increase asthma awareness, educate people on how to avoid environmental asthma triggers, partner with community stakeholders, and help ...

core  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Sustainability of evidence based interventions implemented in CDC's colorectal cancer control program. [PDF]

Implement Sci Commun
Sharma KP, DeGroff A, Beckman M, Juzhong S, Sallyann CK, Djenaba J.   +5 more
europepmc   +1 more source

National viral hepatitis control program in India: Call for update. [PDF]

J Family Med Prim Care, 2023
Pandey P, Roy A, Bhadoria AS.
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

The effectiveness of malaria camps as part of the malaria control program in Odisha, India. [PDF]

Sci Rep, 2023
Ompad DC, Padhan TK, Kessler A, Tozan Y, Jones AM, van Eijk AM, Sullivan SA, Haque MA, Pradhan MM, Mohanty S, Carlton JM, Sahu PK.   +11 more
europepmc   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Algerian Tuberculosis Control Program: 60 Years of Successful Experience. [PDF]

Cureus
Bentata K, Alihalassa S, Gharnaout M, Bennani MA, Berrabah Y.   +4 more
europepmc   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Control and mitigation of dengue and Zika virus transmission in a hospital in Recife, Brazil: a successful experience with an integrated control program against Aedes aegypti. [PDF]

Parasit Vectors
Candida-Silva HE, Ferreira HRP, Mendonça JA, da Silva RA, Krokovsky L, Martins LO, Barbosa KEDS, Ribeiro FJ, de Oliveira CMF, Ayres CFJ, Paiva MHS, de Melo-Santos MAV.   +11 more
europepmc   +1 more source