Results 101 to 110 of about 23,447,263 (353)

Does additional support provided through e-mail or SMS in a Web-based Social Marketing program improve children’s food consumption? A Randomized Controlled Trial [PDF]

, 2018
Natalie Rangelov, Sara Della Bella, Pedro Marques‐Vidal, L. Suzanne Suggs   +3 more
openalex   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

The effect of control strategies to reduce social mixing on outcomes of the COVID-19 epidemic in Wuhan, China: a modelling study

Lancet Public Health, 2020
Kiesha Prem, Yang Liu, T. Russell, A. Kucharski, R. Eggo, Nicholas Davies, Stefan Samuel Carl A B James D Sam Hamish Alicia Billy J Flasche Clifford Pearson Munday Abbott Gibbs Rosel, S. Flasche, S. Clifford, Carl A. B. Pearson, J. Munday, S. Abbott, H. Gibbs, A. Roselló, B. Quilty, T. Jombart, F. Sun, Charlie Diamond, A. Gimma, K. van Zandvoort, S. Funk, C. Jarvis, W. Edmunds, N. Bosse, J. Hellewell, M. Jit, P. Klepac   +26 more
semanticscholar   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Internación compulsiva de usuarios de crack para el tratamiento de la dependencia: una revisión sistemática de la literatura

Memorias del Instituto de Investigaciones en Ciencias de la Salud, 2019
El estudio tuvo como objetivo discutir los conflictos de la internación compulsiva de consumidores de crack. Se realizó una revisión sistemática sobre el tratamiento compulsivo. La búsqueda fue realizada en las bases de datos: Scopus, PubMed, SciELO, Web
Aldo Pacheco Ferreira, Priscila Marcia Costa Assumpção Silva, Marluce Rodrigues Godinho, Regina Maria de Carvalho Erthal, Maria Helena Barros de Oliveira, Marcos Besserman Vianna   +5 more
doaj  

Continuous Additive Peer Review: A New System to Control Social Loafing in Group Projects [PDF]

, 2010
Amit Poddar
openalex   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

El corregidor de naturales y el control económico de las comunidades: cambios y permanencias en la provincia de Santafé siglo XVIII

Anuario Colombiano de Historia Social y de la Cultura, 1992
Los corregidores como primera autoridad judicial, representaron además un papel importante como punto de articulación entre la inflexibilidad de ley escrita y las necesidades económicas de la comunidad. Se pretende demostrar que el manejo del poder en el
Marta Herrera Ángel
doaj  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source