Results 101 to 110 of about 1,948,952 (310)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Anticomunismo y control social en Chile, la experiencia de los trabajadores del carbón en Lota y Coronel, a mediados del siglo XX.

open access: yesRevista de Historia Social y de las Mentalidades, 2013
En los inicios de la década de 1940 la región del carbón en Chile estaba fuertemente influenciada por el Partido Comunista, situación que se contradecía, de acuerdo a los empresarios y autoridades nacionales, con el carácter estratégico de aquella ...
Hernán Venegas Valdebenito
doaj  

Public social services’ encounters with irregular migrants in Sweden : amid values of social work and control of migration

open access: yes, 2012
This article outlines Public Social Services’ encounters with irregular migrants in Sweden from the perspectives of institutional and street-level bureaucrats.
Björngren Cuadra, Carin, Staaf, Annika
core  

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Bridging the islands of society : modeling delinquency prevention through optimization of social support

open access: yes, 2011
The purpose of the meta-analysis is to present a theoretical model of social work interventions within the process of juvenile delinquency prevention. The study approaches delinquency prevention as the process of increasing the amount of social support ...
Rimkus, Valdas
core  

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Apuntes sobre la comunidad gitana española: Breves trazos de su historia en conexión con el contexto europeo.

open access: yesDiálogos, 2011
El trabajo que presentamos a continuación hace un recorrido por la historia del pueblo gitano desde su aparición en tierras hispanas, de lo que se tiene constancia desde el siglo XV, hasta la actualidad.
Ana Esmeralda Rizo López
doaj  

Home - About - Disclaimer - Privacy