Results 131 to 140 of about 23,447,263 (353)

Low Self-Control, Social Learning, and Texting while Driving. [PDF]

open access: yesAm J Crim Justice, 2019
Meldrum RC, Boman JH, Back S.
europepmc   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Manifestaciones del bandolerismo rural y de la acción estatal en la Provincia de Santa Fe. Un caso particular: la trayectoria delictiva de los hermanos Alarcón (1865-1871)

open access: yesHistoria Regional, 2018
A partir de la reconstrucción del comportamiento delictivo de dos sujetos del sur santafesino durante el transcurso de la segunda mitad del siglo XIX, nos proponemos analizar las formas de acción que se llevaron a cabo desde el Estado Provincial a los ...
Jose Miguel Larker
doaj  

Effect of a Job Demand-Control-Social Support Model on Accounting Professionals' Health Perception. [PDF]

open access: yesInt J Environ Res Public Health, 2018
Del Pozo-Antúnez JJ   +3 more
europepmc   +1 more source

Enhancing Pragmatic Language skills for Young children with Social communication difficulties (E-PLAYS-2) trial: study protocol for a cluster-randomised controlled trial evaluating a computerised intervention to promote communicative development and collaborative skills in young children [PDF]

open access: gold
Suzanne Murphy   +12 more
openalex   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

El complejo establecimiento del orden de policía en una sociedad de frontera. Manizales 1853-1871

open access: yesRevista de Antropología y Sociología Virajes, 2014
Este artículo estudia las dificultades del establecimiento de un orden de policía en la parroquia de Manizales  entre 1853 y 1871. Las fuentes utilizadas fueron los sumarios de corrección de policía.
Edwin Monsalvo Mendoza   +1 more
doaj  

Interaction between Social Norms and Law as Control Mechanisms in the Institution of Marriage in India

open access: green, 2013
Devi Jagani   +4 more
openalex   +1 more source

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