Results 101 to 110 of about 29,629,025 (336)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Longitudinal Protection of Grid-Forming New Energy Outgoing Lines Based on Composite Sequence Current Characteristics

Zhongguo dianli
The access of grid-forming new energy centralized transmission system has significantly changed the fault characteristics of the grid, and the traditional longitudinal protection is prone to sensitivity reduction or even refusal risk when the ...
Song YUAN, Zhao GE, Jiajie Tang, Jiabao MEI   +3 more
doaj   +1 more source

Multi-criteria decision analysis (MCDA) for control of transboundary livestock diseases using the example of the 2010/11 foot-and-mouth disease (FMD) outbreak in the Republic of Korea : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Veterinary Science at Massey University, Manawatū [PDF]

, 2015
Decisions regarding transboundary livestock disease control strategies differ from personal decisions, such as buying groceries, in important ways: the stakes are high and the outcome of a decision will affect people in different fields.
Kim, EuTteum
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Automatic Neutral-section Passing Control for HXD1C Electric Locomotive

机车电传动, 2015
The characteristic and principles of HXD1C electric locomotive automatic neutral-section passing control were introduced.Strategy of real-time traction power reduction slope was given to resolve the unbalance of traction power adjustment below fixed ...
WANG Yu, LI Peng, YAN Gang, JIANG Fan
doaj  

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Control Strategy of Ground Automatic Neutral Section Passing for AC Drive Train

机车电传动, 2019
Ground automatic neutral section passing technology has become an effective method to improve speed, the transportation efficiency and capacity of high-speed and heavy-haul railway, and the control strategy adopted by trains is the key to give full play ...
Wenguang LUO, Ping HE, Zhixue ZHANG, Yun PENG, Jingyu HU, Gang FU   +5 more
doaj  

Design and Experimental Research on a New Integrated EBS with High Response Speed

World Electric Vehicle Journal
With the development of the automotive industry, the performance of commercial vehicle braking systems is crucial for road traffic safety. However, traditional braking systems are no longer able to meet the growing demand for response speed, control ...
Feng Chen, Zhiquan Fu, Baoxiang Qiu, Xiaoyi Song, Gangqiang Chen, Zhanming Li, Qijiang He, Guo Lu, Xiaoqing Sun   +8 more
doaj   +1 more source