Results 111 to 120 of about 29,629,025 (336)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
EnergiesGrid-forming (GFM) energy storage can be utilized as a backup power source for the power grid to ensure the security of the power grid. GFM energy storage can also enhance the strength of the power grid and improve its stability.
Chi Tian +4 more
doaj +1 more source
Integrated Control Strategies Supporting Autonomous Functionalities in Mobile Robots [PDF]
Journal of Systemics, Cybernetics and Informatics, 2006 High-level intelligence allows a mobile robot to create and interpret complex world models, but without a precise control system, the accuracy of the world model and the robot's ability to interact with its surroundings are greatly diminished.
Brandon Sights +4 more
doaj
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
, 2015 This chapter studies control strategies. Control strategies are listed and explained. It focuses on modeling vaccination in single-strain and multistrain diseases. Different modes of introducing vaccination in models are shown. Imperfect vaccination as a mechanism leading to backward bifurcation and strain replacement is explained.
openaire +2 more sources
MATHEMATICAL MODELLING OF SMOKING BEHAVIOR: TREATMENT AND PREVENTION OPTIMAL CONTROL
BarekengSmoking remains a critical global public health challenge, with both traditional tobacco use and the rising prevalence of e-cigarettes contributing to significant morbidity and mortality. This study introduces a novel mathematical model that captures the
Ananda Noersena +3 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Kongzhi Yu Xinxi Jishu, 2020 Safety distance parameter is one of the most important parameters in the control strategy of automatic emergency braking system(AEBS). This paper introduced the control strategy of the automatic emergency braking system and the calculation model of ...
ZHAO Chenguang +2 more
doaj
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source