Results 111 to 120 of about 14,399,623 (303)
National Rice Development Strategy 2008-2018 [PDF]
, 2008 This strategy sets the vision, mission, objectives and strategies that Ministry will pursue in ten years with the aim of facilitating growth and development of the rice sub-sector. It will form the basis of which work plans will be formulated at national
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Strategy for Community Health 2014-2019: Transforming health: Accelerating the attainment of health goals [PDF]
, 2014 Kenya Vision 2030 emphasizes preventive health care and health promotion to improve health care and reduce the burden of illness in the community. In 2006, the Ministry of Health developed and adopted the community health strategy as a core component of ...
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, 2015 This chapter studies control strategies. Control strategies are listed and explained. It focuses on modeling vaccination in single-strain and multistrain diseases. Different modes of introducing vaccination in models are shown. Imperfect vaccination as a mechanism leading to backward bifurcation and strain replacement is explained.
openaire +2 more sources
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
, 2015 To assist in the development of the National Diabetes Strategy, the Federal Government has released this consultation paper and invites submissions from the public. Purpose This document has been written by the National Diabetes Strategy Advisory Group
National Diabetes Strategy Advisory Group
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FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Taita Taveta County Fiscal Strategy Paper 2014
, 2014 The 2014 County Fiscal Strategy Paper is the first of its kind under the devolved system of Governance in Taita Taveta County, which aims at ensuring an effective linkage between policies, planning and budgeting.
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