Results 121 to 130 of about 14,399,623 (303)
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
National Wildlife Strategy 2018-2030
, 2018 Kenya ranks highly as one of the biodiversity rich country’s in the World. The iconic wildlife and the diverse conservation areas are among the countries most valuable assets.
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Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Kenya Health Sector Referral Strategy 2014-2018
, 2014 The overall goal of the Kenya Health Sector Referral Strategy is to improve client access to referral. The objectives of the strategy are to realise improved capacity of health providers to identify clients who require referral, develop protocols that ...
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Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
The Performance Implications of Fit Among Environment, Strategy, Structure, Control System and Social Performance [PDF]
, 2013 Purpose – The paper examined concept of corporate performance. The paper seeks to examine the impact of corporate social performance on the relationship among business environment, strategy, organization, and control system and corporate performance.
Fauzi, Hasan
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An Active Power Filter Based on Improved Half-bridge Main Circuit
Kongzhi Yu Xinxi Jishu, 2013 Via the analysis of double-inductance half-bridge circuit, a novel active power filter was introduced based on improved halfbridge topology, which can eliminate the hidden faults of bridge arm shoot-through in traditional active power filter topology. It
WANG Zhihui +3 more
doaj
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
National Community Health Digitization Strategy 2020-2025
, 2020 Despite its importance, the delivery of community health continues to suffer from weak data collection and reporting tools. This hinders the optimal use of community-level data to inform public health response and resource allocation.
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Nyeri County Fiscal Strategy Paper 2015 [PDF]
, 2015 The preparation of the CFSP, 2015 is a collaborative effort of the county departments with overall coordination by the Finance and Economic Planning department.
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