Bifunctional <i>Aloe-Birch</i> Extracts for Green Silver Nanoparticle Synthesis and Synergistic Antimicrobial Microneedles Toward Infected Wound Healing. [PDF]
Zhang S +5 more
europepmc +1 more source
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
Controlled aqueous nanoassembly-driven fully automated Fmoc solid-phase peptide synthesis (SPPS) with in-water coupling. [PDF]
Hojo K +6 more
europepmc +1 more source
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata +3 more
wiley +1 more source
Chronic Ankle Instability and Low Back Pain: A Narrative Review With a Conceptual Framework Linking Distal and Proximal Sensorimotor Dysfunction. [PDF]
Abdallah EA +2 more
europepmc +1 more source
Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla +10 more
wiley +1 more source
Ultrasonic irradiation in the synthesis of nanohydroxyapatite: a chemically friendly technique for improving hemocompatibility and antibiofilm applications. [PDF]
Mendoza Turmero J +8 more
europepmc +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Efficacy of a Large Language Model Data Extraction System in Evidence Reviews for Emerging Infectious Diseases: A Randomized Crossover Trial. [PDF]
Ishikane M +5 more
europepmc +1 more source

