Results 131 to 140 of about 1,558,340 (318)

PROMIS: a statistical-parametric speech synthesis system with prominence control via a prominence network [Elektronisk resurs] [PDF]

open access: yes, 2019
We implement an architecture with explicit prominence learning via a prominence network in Merlin, a statistical-parametric DNN-based text-to-speech system.
Gustafson, Joakim,   +3 more
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Hormonal control of protein synthesis in the fat body of Leptinotarsa decemlineata [PDF]

open access: yes, 1979
This thesis deals with the hormonal control of protein synthesis in the female fat body of Leptinotarsa decemlineata Say. The results are discussed in relation to reproduction (obtained by rearing under long day conditions) and the preparation for ...
Dortland, J.F.
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Robustness of HMM-based speech synthesis [PDF]

open access: yes, 2008
As speech synthesis techniques become more advanced, we are able to consider building high-quality voices from data collected outside the usual highly-controlled recording studio environment.
Ling, Z.   +5 more
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

On the optimal synthesis problem for control systems

open access: yesИзвестия Иркутского государственного университета: Серия "Математика", 2015
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
R. Gabasov, F.M. Kirillova
openaire   +2 more sources

Dynamic Event‐Triggered Consensus for Switched Nonlinear Systems in Intelligent Manufacturing

open access: yesIET Collaborative Intelligent Manufacturing
Multiagent cooperative control enhances system efficiency through the facilitation of distributed collaboration, demonstrating significant applications in intelligent manufacturing.
Shanyan Hu   +4 more
doaj   +1 more source

Spatializing Timbre with Corpus-Based Concatenative Synthesis [PDF]

open access: yes, 2010
Corpus-based concatenative synthesis presents unique possibilities for the visualization of audio descriptor data. These visualization tools can be applied to sound diffusion in the physical space of the concert hall using current spatialization ...
Einbond, A.   +5 more
core  

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