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The influence of additives such as natural-based plasticiser acetyl tributyl citrate (ATBC), CaCO3 and lignin-coated cellulose nanocrystals (L-CNC) on the biodegradation of polylactic acid (PLA) biocomposites was studied by monitoring microbial metabolic
Pavel Brdlik +2 more
exaly +2 more sources
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Biodegradable microparticles for the controlled delivery of oligonucleotides
International Journal of Pharmaceutics, 2002Microspheres allowing the controlled release of the model oligonucleotide pdT16 were designed. The oligonucleotide, alone or associated with polyethylenimine (PEI) at different nitrogen/phosphate ratios, was encapsulated within poly(lactide-co-glycolide) microspheres prepared by the multiple emulsion-solvent evaporation technique.
DE ROSA, GIUSEPPE +4 more
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Biodegradable polymersomes for controlled drug release
Journal of Controlled Release, 2008Hydrophilic fluorescein isothiocyanate-dextran (FD, mol. weight 4000 g/mol) could be readily incorporated in polymersomes (PS) made of different amphiphilic biodegradable block copolymers based on PEG-PDLLA, PEG-PCL, and PEG-PTMC. The FD release from these polymersomes in PBS at 37 °C was complete within approximately 10 days.
Zhou, W., Feijen, Jan
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Biodegradable Polysaccharides for Controlled Drug Delivery
ChemPlusChem, 2016AbstractPolysaccharides are ideal candidates for drug delivery and biomedical applications as they are easily obtained from natural sources. Furthermore, they can be subjected to a wide range of chemical and enzymatic reactions, they have biocompatible and biodegradable properties and have inherently low immunogenicity.
Janarthanan, Pushpamalar +3 more
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A biodegradable filament for controlled drug delivery
Journal of Controlled Release, 2009Biodegradable filaments (diameters of 250-300 microm) for the controlled delivery of dexamethasone or levofloxacin are described. Filaments are prepared by wet-spinning solutions of poly(lactide-co-glycolide) (PLGA) and drug dissolved in dimethyl sulfoxide (DMSO) into a coagulation bath of water.
Mack, Brendan C. +2 more
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Controlled Synthesis of Biodegradable Polyesters
2001The application of new initiators for the ring-opening polymerization of cyclic esters has markedly improved the macromolecular engineering of biodegradable polyesters. A wide variety of complex macromolecular architectures can nowadays be prepared using these initiators.
Dijkstra, Pieter J. +3 more
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The Control of Biodegradation of Gutting Fluid
Industrial Lubrication and Tribology, 1970THE PURPOSE of the following report is to describe a trial set up to test the practicability of extending the effective working life of a cutting emulsion and to investigate the nature of the problems associated with biochemical breakdown. The trial covered a period of more than two years, with a break of two months in the middle, when the treatment ...
E.H. Littler, B.E. Purkiss
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Biodegradable Nanobowls with Controlled Dents
ACS Macro LettersNanobowls show promising potential in biomedical applications, such as bioimaging, cargo delivery, and disease theranostics, due to their unique concave structure and interior cavities. However, the lack of biodegradable nanobowls with manipulable size (especially the dent size) still exists as an obstacle for their in-depth exploration and application
Jinhui Jiang +7 more
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Biodegradable Chitosan Matrix for the Controlled Release of Steroids
Biomaterials, Artificial Cells and Immobilization Biotechnology, 1991Chitosan, a polysaccharide, having structural characteristics similar to glycosaminoglycans, seems to be nontoxic and bioabsorbable. This study highlights the use of chitosan matrix for controlled drug delivery systems. The steroid drugs, namely testosterone, progesterone and beta-oestradiol were mixed with chitosan and the films were prepared by ...
T, Chandy, C P, Sharma
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Polymer Encapsulation of Magnesium to Control Biodegradability and Biocompatibility
Journal of Nanoscience and Nanotechnology, 2014Clinical utility of biodegradable magnesium implants is undermined by the untimely degradation of these materials in vivo. Their high corrosion rate leads to loss of mechanical integrity, peri-implant alkalization and localised accumulation of hydrogen gas. Biodegradable coatings were produced on pure magnesium using RF plasma polymerisation.
Bazaka, Kateryna +2 more
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