Results 271 to 280 of about 2,358,784 (358)

Magnetic scaffold for drug targeting: evaluation of cephalosporins controlled release profile

, 2011
Dan Eduard Mihăiescu, Alexandru Mihai Grumezescu, Paul Cătălin Balaure, Diana Mogosanu, Vanessa Traistaru, J Banerjee, R Narendhirakannan, J Andeani, H Kazemi, S Mohsenzadeh, A Safavi, K Satyavani, T Ramanathan, S Gurudeeba, A Slav, R Popovici, C Mihai, E Seftel, P Rotinberg, V Popovici, A Voicu, I Alexa, R Popovici, M Ignat, E Popovici, V Voicu, A, M Mahmoodi, M Khosroshahi, F Atyabi, S Vlad, C Ciobanu, R Gradinaru, L Gradinaru, A Nistor, J Neamtu, N Verga, C Saviuc, A Grumezescu, A Holban, C Bleotu, C Chifiriuc, P Balaure, V Lazar, C Saviuc, A Grumezescu, A Holban, C Chifiriuc, D Mihaiescu, V Lazar, Ming-Jenn Chen, Yen-Yi Chu, Pei-Heng Lai, Ya-Min Cheng, Yi-Chiang Hsu, S Fatahian, D Shahbazi, M Pouladian, M Yousefi, Amiri Gh, Z Shahi, M Shahabadi, H Jahanbakhsh, A Grumezescu, D Mihaiescu, D Mogoanu, M Chifiriuc, V Lazr, I Clugrescu, V Tristaru, M Ghazi, M Izadifard, M Bagherzadeh, M Chirea, E Pereira, C Pereira, F Silva, M Chirea, E Pereira, C Pereira, F Silva, A Grumezescu, E Ilinca, C Chifiriuc, D Mihaiescu, P Balaure, V Traistaru, G Mihaiescu, D Mihaiescu, A Grumezescu, D Mogosanu, V Traistaru, P Balaure, A Buteica, A Grumezescu, G Voicu, C Saviuc, A Holban, D Mihaiescu, C Chifiriuc   +99 more
openalex   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Recent progress in antimicrobial strategies of controlled-release nanomaterials for secondary caries. [PDF]

Front Cell Infect Microbiol
Wang Y, Du X, Jia Y, Qin L, Liu F, Cai Y, Wang S.   +6 more
europepmc   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Chitosan Derivatives Associated with Ceftazidime: Study of Controlled Release and Antibacterial Activity. [PDF]

ACS Omega
Reis LDS, Bezerra RDS, Barreto HM, Osajima JA, Silva-Filho EC.   +4 more
europepmc   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Redox-Switchable Poly-Lewis Acids Allow the Controlled Release of Guests. [PDF]

Angew Chem Int Ed Engl
Klingsiek MJ, Vishnevskiy YV, Buth J, Lamm JH, Neumann B, Stammler HG, Mitzel NW.   +6 more
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Biopolymer-based multilayer capsules for protection and controlled release of Pseudomonas fluorescens T17-4 and Bacillus velezensis VRU1. [PDF]

Sci Rep
Saberi Riseh R, Fathi F.
europepmc   +1 more source