Results 101 to 110 of about 41,044,287 (345)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

TOOLS FOR EVALUATION OF CONTROLLING SYSTEM

open access: yesСтатистика и экономика, 2016
Scientific recognition and implementation of any new economic theory or concept depend significantly on the mathematical formalization which they allow.
Vladimir P. Bogko   +3 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Peculiarities of Traction Asynchronous Electric Drive Application as a Part of Rail Transport

open access: yesМеханика машин, механизмов и материалов, 2012
Development of asynchronous electric drive and its application on transport vehicles, particularly as a part of trams is treated. Introduction of modeling results for twin-engined drive is provided.
V.M. Korol
doaj  

A Multiobjective Optimization Algorithm for Fluid Catalytic Cracking Process with Constraints and Dynamic Environments

open access: yesMathematics
The optimization problems in a fluid catalytic cracking process with dynamic constraints and conflicting objectives are challenging due to the complicated constraints and dynamic environments.
Guanzhi Liu, Xinfu Pang, Jishen Wan
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Chain Controllability of Linear Control Systems

open access: yesSIAM Journal on Control and Optimization
For linear control systems with bounded control range, chain controllability properties are analyzed. It is shown that there exists a unique chain control set and that it equals the sum of the control set around the origin and the center Lyapunov space of the homogeneous part.
Fritz Colonius   +2 more
openaire   +2 more sources

Control apparatus for spectral energy source [PDF]

open access: yes, 1967
Automatic light-controlling system for dc arc emission spectrographs controls the vaporization rate of the sample and stabilizes the dc arc. The output energy is regulated such that advantage can be taken of the highly sensitive dc arc source without ...
Gordon, W. A.
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

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