Results 111 to 120 of about 41,044,287 (345)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Accounting and Controlling Business Management System [PDF]
ACTA VŠFS, 2016 The author examines an efficient accounting and management system that gives a true picture of an economic reality with a direct link to the consumer to achieve maximum effectiveness of financial planning and the business as a whole ...
David Mareš
doaj
Controlling the British Gas Grid System
Measurement + Control, 1985 This paper was orginally presented at the East of Scotland Section of the Institute of Measurement and Control on 2 April 1985.
A D N March
doaj +1 more source
The enteric nervous system : new developments and emerging concepts [PDF]
, 2011 The enteric nervous system (ENS) is an integrative neuronal network, organized in two ganglionated plexuses, myenteric and submucosal, composed of neurons and enteric glial cells, controlling the activity of the smooth muscle of the gut, mucosal ...
Garzia Zizzo, Maria +2 more
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Prerequisites for the establishment and development of financial controlling
Економіка, управління та адмініструванняThe article is devoted to the identification of historical prerequisites for the formation and development of financial controlling. It was determined that controlling in general and financial controlling, in particular, were studied within the framework
S.М. Ratushnyi
doaj +1 more source
Insulated conjugated bimetallopolymer with sigmoidal response by dual self-controlling system as a biomimetic material. [PDF]
Nat Commun, 2020 Masai H +7 more
europepmc +1 more source
Grain refinement control in TIG arc welding [PDF]
, 1975 A method for controlling grain size and weld puddle agitation in a tungsten electrode inert gas welding system to produce fine, even grain size and distribution is disclosed.
Iceland, W. F., Whiffen, E. L.
core +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source