Results 31 to 40 of about 286,683 (311)
The role and implications of mammalian cellular circadian entrainment
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
ASSESSMENT OF THE E 920 ADDITIVE (L - CYSTEINE) IN RELATION TO SOME PROBLEMS OF MODERN FOOD INDUSTRY [PDF]
This paper aims to assess the current state of knowledge about the use of L - cysteine in food industry, regarding certain cultural, legal, technological, toxicological, and other aspects that influence the attitude of the consumerstowards food. Use of L
Radiana Maria TAMBA BEREHOIU +2 more
doaj
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
Une production dystopique ? Images, discours et conditions de travail dans l’industrie vidéoludique
There years after the controversial release of Cyberpunk 2077 (CD Projekt RED, 2020) and its return to favor with the Phantom Liberty extension, this article returns to the causes and consequences of this scandal.
Flavie Falais
doaj +1 more source
Through an analysis of a controversy about the accusations of “self-transformation” and “self-evolution”, formulated by the Vietnamese Communist Party (VCP) against Chu Hảo, an intellectual-member of the VCP, this paper aims to test the hypothesis ...
Thi Thanh Phuong Nguyen-Pochan
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Trace element zinc metabolism and its relation to tumors
Zinc is an essential trace element in the human body, playing a crucial role in cellular metabolism.Dysregulation of zinc homeostasis can lead to abnormal cellular metabolism, contributing to diseases and closely related to tumor development.
Guiping Yao +8 more
doaj +1 more source
The Controversies Surrounding Acne and Suicide: Essential Knowledge for Clinicians [PDF]
Nihit Gupta, Mayank Gupta
openalex +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source

