Results 31 to 40 of about 226,361 (261)
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Argumentation et Analyse du Discours, 2023 This “critical reflection” examines the way in which Jean-Claude Guerrini's two books (2019 and 2022) Values in Argument: The Legacy of Chaïm Perelman and Value Conflicts and Bullfighting: An Argumentative Study of Controversy deal with the argumentation
Roselyne Koren
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Une production dystopique ? Images, discours et conditions de travail dans l’industrie vidéoludique
Images du Travail, Travail des ImagesThere years after the controversial release of Cyberpunk 2077 (CD Projekt RED, 2020) and its return to favor with the Phantom Liberty extension, this article returns to the causes and consequences of this scandal.
Flavie Falais
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
La exégesis bíblica en la polémica contra judíos
Mélanges de la Casa de Velázquez, 2019 In the year 1520, Don Martin Garcia gathered and printed a selection of 156 of his sermons, the main objective of which was both political and religious.
Manuel Montoza Coca
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Trace element zinc metabolism and its relation to tumors
Frontiers in EndocrinologyZinc is an essential trace element in the human body, playing a crucial role in cellular metabolism.Dysregulation of zinc homeostasis can lead to abnormal cellular metabolism, contributing to diseases and closely related to tumor development.
Guiping Yao +8 more
doaj +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Genre, Sexualité et Société, 2017 This article investigates the Catholics opposition to the ratification of the Additional Protocol to the African Charter on Human and Peoples’ Rights on the Rights of Women in Africa (Maputo Protocol). This Protocol states among other things the right of
Lison Guignard
doaj +1 more source