Results 41 to 50 of about 348,009 (316)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Building On Controversy : Developing Architectural Dialogues on Controversial Sites

open access: yes, 2020
This thesis explores how controversial sites that are in stasis, like the old memorial library in Halifax, can be transformed into architecture. As the public becomes more involved in architectural design process the occurrence of sites in stasis like ...
Ramadan, Makenzie
core  

Une production dystopique ? Images, discours et conditions de travail dans l’industrie vidéoludique

open access: yesImages du Travail, Travail des Images
There years after the controversial release of Cyberpunk 2077 (CD Projekt RED, 2020) and its return to favor with the Phantom Liberty extension, this article returns to the causes and consequences of this scandal.
Flavie Falais
doaj   +1 more source

Résistances catholiques au protocole de Maputo. Mobilisations et controverses autour de la libéralisation de l’avortement en Afrique

open access: yesGenre, Sexualité et Société, 2017
This article investigates the Catholics opposition to the ratification of the Additional Protocol to the African Charter on Human and Peoples’ Rights on the Rights of Women in Africa (Maputo Protocol). This Protocol states among other things the right of
Lison Guignard
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Revisiting the Althusser/E. P. Thompson-Controversy: Towards a Marxist theory of communication [PDF]

open access: yes, 2019
This essay revisits the controversy between Louis Althusser’s Marxist structuralism and Edward P. Thompson’s Marxist humanism. It draws conclusions from this controversy for the foundations of the Marxist theory of communication.
Fuchs, Christian
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Trace element zinc metabolism and its relation to tumors

open access: yesFrontiers in Endocrinology
Zinc is an essential trace element in the human body, playing a crucial role in cellular metabolism.Dysregulation of zinc homeostasis can lead to abnormal cellular metabolism, contributing to diseases and closely related to tumor development.
Guiping Yao   +8 more
doaj   +1 more source

Manipulation et information fictionnelle

open access: yesCommunication, 2010
On December 13, 2006, Radio Télévision Belge Francophone (RTBF) interrupted its regular programming with a special bulletin to report/broadcast a false news story : Flanders had seceded and unilaterally declared its independence.
Jean-Paul Dufiet
doaj   +1 more source

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