Results 41 to 50 of about 230,844 (269)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Trace element zinc metabolism and its relation to tumors

open access: yesFrontiers in Endocrinology
Zinc is an essential trace element in the human body, playing a crucial role in cellular metabolism.Dysregulation of zinc homeostasis can lead to abnormal cellular metabolism, contributing to diseases and closely related to tumor development.
Guiping Yao   +8 more
doaj   +1 more source

Managing Relational Legacies: Lessons from British Columbia, Canada

open access: yesAdministrative Sciences, 2014
Issues related to company-community relations and the social license to operate have emerged as strategic business issues. This paper aims to contribute to the growing body of research on long-term company-community relations.
Sofiane Baba, Emmanuel Raufflet
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Défense et illustration de l’argumentation des valeurs : réflexions à partir des travaux de Jean-Claude Guerrini

open access: yesArgumentation et Analyse du Discours, 2023
This “critical reflection” examines the way in which Jean-Claude Guerrini's two books (2019 and 2022) Values in Argument: The Legacy of Chaïm Perelman and Value Conflicts and Bullfighting: An Argumentative Study of Controversy deal with the argumentation
Roselyne Koren
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

ASSESSMENT OF THE E 920 ADDITIVE (L - CYSTEINE) IN RELATION TO SOME PROBLEMS OF MODERN FOOD INDUSTRY [PDF]

open access: yesScientific Papers Series : Management, Economic Engineering in Agriculture and Rural Development, 2013
This paper aims to assess the current state of knowledge about the use of L - cysteine in food industry, regarding certain cultural, legal, technological, toxicological, and other aspects that influence the attitude of the consumerstowards food. Use of L
Radiana Maria TAMBA BEREHOIU   +2 more
doaj  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

L’heure du conte drag au Québec

open access: yesCommunication
This article draws on a press analysis to identify the main frameworks used to shape Québec controversy over drag story time in the spring of 2023. It identifies nine frameworks divided into three main areas: children’s well-being and safety, protection ...
David Myles   +3 more
doaj   +1 more source

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