Results 61 to 70 of about 410,044 (303)
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Epilogue: Controversy and Fetal Research : The Swedish Case
This epilogue draws together and expands on discussions in the volume in order to highlight the issue of public controversy around the scientific uses of fetal material during the Swedish postwar period.
Jülich, Solveig,
core +1 more source
Resolving Controversy in the European Union
, 2011 How does the EU resolve controversy when making laws that affect citizens? How has the EU been affected by the recent enlargements that brought its membership to a diverse group of twenty-seven countries?
Robert Thomson, Thomson, Robert
core +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Kontroversi Doktrin Tarekat dalam Puisi Sufistik Karya Syaikh Isma‘il al-Minangkabawi
Buletin Al-Turas, 2015 Abstrak Tarekat adalah gerakan dan aktifitas sufistik yang terwujud dalam bentuk lembaga dan organisasi. Sebagai sebuah organisasi keagamaan yang lebih berorientasi pada aktifitas menempuh perjalanan ruhaniyah dan spiritual, maka diperlukan adanya ...
Syofyan Hadi
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Frontiers in Psychology, 2018 Research on attitudinal ambivalence is flourishing, but no research has studied how others perceive its expression. We tested the hypothesis that the expression of attitudinal ambivalence could be positively valued if it signals careful consideration of ...
Vincent Pillaud +2 more
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Advances in Psychiatric Diagnosis: Past, Present, and Future
Behavioral Sciences, 2017 This editorial examines controversies identified by the articles in this special issue, which explore psychopathology in the broad history of the classification of selected psychiatric disorders and syndromes over time through current American criteria ...
Carol S. North, Alina M. Surís
doaj +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source