Results 51 to 60 of about 348,009 (316)
On the controversiality of AI: The controversy is not the situation
Big Data & SocietyDo public controversies about AI matter? Can they really make a difference to how AI is taken up or imposed on society? This introduction to the Special Issue on Analysing Articifial Intelligence Controversies (?) discusses how the contributing articles and commentaries address this question through original research and critical reflection.
Noortje Marres +3 more
openaire +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Managing Relational Legacies: Lessons from British Columbia, Canada
Administrative Sciences, 2014 Issues related to company-community relations and the social license to operate have emerged as strategic business issues. This paper aims to contribute to the growing body of research on long-term company-community relations.
Sofiane Baba, Emmanuel Raufflet
doaj +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Resolving Controversy in the European Union
, 2011 How does the EU resolve controversy when making laws that affect citizens? How has the EU been affected by the recent enlargements that brought its membership to a diverse group of twenty-seven countries?
Robert Thomson, Thomson, Robert
core +1 more source
L’heure du conte drag au Québec
CommunicationThis article draws on a press analysis to identify the main frameworks used to shape Québec controversy over drag story time in the spring of 2023. It identifies nine frameworks divided into three main areas: children’s well-being and safety, protection ...
David Myles +3 more
doaj +1 more source
ASSESSMENT OF THE E 920 ADDITIVE (L - CYSTEINE) IN RELATION TO SOME PROBLEMS OF MODERN FOOD INDUSTRY [PDF]
Scientific Papers Series : Management, Economic Engineering in Agriculture and Rural Development, 2013 This paper aims to assess the current state of knowledge about the use of L - cysteine in food industry, regarding certain cultural, legal, technological, toxicological, and other aspects that influence the attitude of the consumerstowards food. Use of L
Radiana Maria TAMBA BEREHOIU +2 more
doaj
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source