Results 71 to 80 of about 286,683 (311)
TMC4 localizes to multiple taste cell types in the mouse taste papillae
FEBS Open Bio, EarlyView.Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Ibero-Americana Pragensia, 2018 The purpose of this essay is to explain the rancor between Cervantes and the Dukes of Villahermosa María Luisa de Aragón and Carlos de Borja (El Quijote, vol. II, capítulos 30-50).
Jack Weiner
doaj +1 more source
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
The next controversy in genetic testing: clinical data as trade secrets? [PDF]
, 2012 Robert Cook‐Deegan +3 more
openalex +1 more source
FEBS Open Bio, EarlyView.Patatin domain‐containing (phospho)lipases are lipid‐hydrolyzing enzymes central to metabolism, membrane remodeling, and signaling. Their activity relies on precise co‐activation mechanisms involving protein–protein interactions and conformational rearrangements.
Noopur Dubey +2 more
wiley +1 more source
Laser physics: Quantum controversy in action [PDF]
, 1999 Willis E. Lamb +3 more
openalex +1 more source
Prediction Model for Etiologic Differentiation of Isolated Vestibular Syndrome in Emergency Settings
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective This study aimed to develop and validate a predictive model for differentiating central from peripheral etiologies in patients with isolated vestibular syndrome (VS). Methods In this multicenter retrospective cohort study, 506 patients with isolated VS from five hospitals were divided into derivation (n = 301) and validation (n = 205)
Guo Wenting +12 more
wiley +1 more source
Controversial Elements: Priority Disputes and the Discovery of Chemical Elements
Substantia, 2019 There are only a limited number of chemical elements and to be credited with the discovery of a new one is therefore considered of great importance. Adding to the honour and fame is that traditionally the discoverer has the right to name the element in ...
Helge Kragh
doaj +1 more source
The transfusion‐related acute lung injury controversy: lessons from heparin‐induced thrombocytopenia [PDF]
, 2015 Theodore E. Warkentin +2 more
openalex +1 more source