Conotoxin Diversity in Chelyconus ermineus (Born, 1778) and the Convergent Origin of Piscivory in the Atlantic and Indo-Pacific Cones. [PDF]
Genome Biol Evol, 2018 Abalde S +3 more
europepmc +1 more source
High-Throughput Identification and Analysis of Novel Conotoxins from Three Vermivorous Cone Snails by Transcriptome Sequencing. [PDF]
Mar Drugs, 2019 Yao G +7 more
europepmc +1 more source
Exploring the mitogenomic of Lottiidae (Patellogastropoda): phylogenetics, gene rearrangement and evolutionary divergence time estimations. [PDF]
BMC GenomicsFeng J, Miao J, Li J, Ye Y.
europepmc +1 more source
Marine Antimicrobial Peptides: Advances in Discovery, Multifunctional Mechanisms, and Therapeutic Translation Challenges. [PDF]
Mar DrugsGao B +5 more
europepmc +1 more source
Synthesis and insecticidal activity of cysteine-free conopeptides from Conus betulinus
Toxicon, 2023The cone snail Conus betulinus is a vermivorous species that is widely distributed in the South China Sea. Its crude venom contains various peptides used to prey on marine worms. In previous studies, a systematic analysis of the peptide toxin sequences from C. betulinus was carried out using a multiomics technique.
Jiao Chen, Bingmiao Gao
exaly +3 more sources
Antioxidant Peptides from the Protein Hydrolysates of Conus betulinus
International Journal of Peptide Research and Therapeutics, 2011The current study aims at the isolation and characterization of the peptides, believed to have antioxidant activity, from Conus betulinus by using different types of enzymes. The body and viscera of C. betulinus were treated with three enzymes viz. trypsin, pepsin and papain to obtain peptide hydrolysates.
Rasool Abdul Nazeer, Nazeer R A
exaly +2 more sources
Isolation and Characterization of Conotoxin bt5a from Conus betulinus
Chinese Journal of Natural Medicines, 2010Abstract Aim To study the chemical constituents of the venom of Conus betulinus that collected from South China Sea. Methods Gel chromatography and HPLC were applied to isolate toxins from the venom of Conus betulinus and a peptide toxin was obtained.
Ji-Sheng Chen
exaly +2 more sources
A Novel Conotoxin from Conus betulinus, κ-BtX, Unique in Cysteine Pattern and in Function as a Specific BK Channel Modulator [PDF]
Journal of Biological Chemistry, 2003 A novel conotoxin, kappa-conotoxin (kappa-BtX), has been purified and characterized from the venom of a worm-hunting cone snail, Conus betulinus. The toxin, with four disulfide bonds, shares no sequence homology with any other conotoxins. Based on a partial amino acid sequence, its cDNA was cloned and sequenced.
Chris Ulens +2 more
exaly +3 more sources
Contryphan-Bt: A pyroglutamic acid containing conopeptide isolated from the venom of Conus betulinus
Toxicon, 2017A new member of the contryphans family was isolated from the venom of Conus betilinus, a vermivorous species distributed in the South China Sea. Its sequence, ZSGCO(D-W)KPWC-NH2 (Z, pyroglutamic acid), was established by a combination of de novo MS/MS sequencing and venom-duct transcriptome sequencing. The occurrence of D-Trp6 was confirmed by chemical
Penggang Han, Ge Yao, Wenjian Wu
exaly +3 more sources