A Novel Conotoxin from Conus betulinus, κ-BtX, Unique in Cysteine Pattern and in Function as a Specific BK Channel Modulator [PDF]
Journal of Biological Chemistry, 2003 A novel conotoxin, kappa-conotoxin (kappa-BtX), has been purified and characterized from the venom of a worm-hunting cone snail, Conus betulinus. The toxin, with four disulfide bonds, shares no sequence homology with any other conotoxins. Based on a partial amino acid sequence, its cDNA was cloned and sequenced.
Chong-Xu, Fan +13 more
openaire +4 more sources
Identification of neuropeptide Y-like conopeptides from the venom of <italic>Conus betulinus</italic> [PDF]
Acta Biochimica et Biophysica Sinica, 2010 Xuechen Wu +3 more
openaire +3 more sources
Ecology and Evolution, Volume 12, Issue 6, June 2022., 2022 Enrich the mitochondrial genome data of Neritidae species. Established the phylogenetic tree of gastropoda. Speculated the separation time of Neritidae species. Abstract Neritids are ancient gastropod species which can live in marine, brackish water, and freshwater environments.
Jing Miao +8 more
wiley +1 more source
Novel conopeptides of the I-superfamily occur in several clades of cone snails [PDF]
, 2004 The I-superfamily of conotoxins represents a new class of peptides in the venom of some Conus species. These toxins are characterized by four disulfide bridges and inhibit or modify ion channels of nerve cells.
Huys, I. +5 more
core +3 more sources
The genome of the venomous snail Lautoconus ventricosus shed light on the origin of conotoxin diversity [PDF]
, 2021 Background: Venoms are deadly weapons to subdue prey or deter predators that have evolved independently in many animal lineages. The genomes of venomous animals are essential to understand the evolutionary mechanisms involved in the origin and ...
Abalde +125 more
core +2 more sources
Mass Spectrometry-based Sequencing of Venom Peptides (Conotoxins) from Vermivorous Cone Snail, Conus Loroisii: Toxicity of its Natural Venom [PDF]
, 2021 Conus loroisii is a marine vermivorous snail found profusely in the southern seas of India. They harbor several toxic peptide components commonly called as ‘conotoxins’. In this study, we have identified and sequenced five conotoxins using proteome based
J, Arun Kumar +4 more
core +2 more sources
Purification of 57kDa Hyaluronidase from the venom of Conus betulinus (Linnaeus, 1758)
, 2022 Abstract The enzyme hyaluronidase cleaves the substrate hyaluronic acid. In the study, hyaluronidase was isolated from the venom gland of C. betulinus and characterised using SDS-PAGE, FTIR, and HPLC. The protein content of crude venom is approximately 4mg/ml, whereas purification with Sepacryl S-100 yielded 0.04mg/ml protein with 0.463TRU/mg ...
Ramachandiran Sivaramakrishnan +2 more
openaire +1 more source
The Evolution of Fangs, Venom, and Mimicry Systems in Blenny Fishes [PDF]
, 2017 Venom systems have evolved on multiple occasions across the animal kingdom, and they can act as key adaptations to protect animals from predators. Consequently, venomous animals serve as models for a rich source of mimicry types, as non-venomous ...
Amanda Nouwens +23 more
core +6 more sources
Conus : First comprehensive conservation red list assessment of a marine gastropod mollusc genus [PDF]
, 2013 Marine molluscs represent an estimated 23% of all extant marine taxa, but research into their conservation status has so far failed to reflect this importance, with minimal inclusion on the authoritative Red List of the International Union for the ...
Carpenter, Kent E. +4 more
core +3 more sources
Evolution: Fangtastic Venoms Underpin Parasitic Mimicry [PDF]
, 2017 Venomous teeth are rare in fishes, which typically utilise spines for defence. A new study reveals the evolutionary origins of fangs and venom in the Nemophini blennies and shows that, in contrast to snakes and lizards, the fangs pre-date the ...
Taylor, Martin I.
core +1 more source