Venomics as a Drug Discovery Platform: Identifying Conopeptides with Pharmacological Activity [PDF]
, 2020 Cone snail venom is a mixture of disulfide-constrained peptides (conotoxins), hormone-like peptides, and proteins that have been ‘weaponized’ for predation and defense.
Grandal, Meghan Kathleen
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High-Throughput Prediction and Design of Novel Conopeptides for Biomedical Research and Development. [PDF]
Biodes Res, 2022 Gao B +7 more
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Mitogenome Characterization of Four Conus Species and Comparative Analysis. [PDF]
Int J Mol Sci, 2023 Wang H, Zhu X, Liu Y, Luo S, Zhangsun D.
europepmc +1 more source
, 2017 dissertationCone snails (genus Conus) have attracted scientific interest for the great neuropharmacological potential of their venoms to treat chronic pain, which consist of a complex mixture of peptides known as conotoxins.
Li, Qing
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Reconstructing the Origins of the Somatostatin and Allatostatin-C Signaling Systems Using the Accelerated Evolution of Biodiverse Cone Snail Toxins. [PDF]
Mol Biol Evol, 2022 Koch TL +8 more
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A toxin-based approach to neuropeptide and peptide hormone discovery. [PDF]
Front Mol Neurosci, 2023 Koch TL +6 more
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Deciphering the transcriptomics of the Conus species' natural venoms [PDF]
, 2022 José Manuel Ramos Morim
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Prospecting for candidate molecules from Conus virgo toxins to develop new biopharmaceuticals. [PDF]
J Venom Anim Toxins Incl Trop Dis, 2022 Mohamed AA, Nabil ZI, El-Naggar MS.
europepmc +1 more source
Genetic Drivers of Diversification in the Conus Adaptive Radiation [PDF]
, 2019 Adaptive radiations offer striking examples of biodiversity. Their rapid diversification is facilitated by adaptive traits, which allow co-occurring species to partition niche space.
Wood, Andrew
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Collaborative Expression: Transcriptomics of Conus virgo Suggests Contribution of Multiple Secretory Glands to Venom Production. [PDF]
J Mol Evol, 2023 Fedosov A +4 more
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