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Studies on conotoxins of Conus betulinus.

Journal of natural toxins, 2000
The biological activity and toxicity of crude venom from Conus betulinus, which was collected from the South China Sea, were studied. The venom shows Ach receptor activity, K+ current effect, and low toxicity. Four peptide components, named BeTXIa, BeTXIb, BeTXIIa, and BeTXIIb, were purified by gel-filtration with Sephadex followed by HPLC, and finally
J S, Chen   +4 more
openaire   +1 more source

Purification and characterization of a new conotoxin from the venom of Conus betulinus

2005
Marine snails belonging to the genus Conus are venomous predators that have developed a unique biochemical strategy for envenoming their prey. Their venom contains a number of small peptides ranging in size from ~13 to 30 amino acid residues. The structures and mode of action of many peptides from Conus venom have been elucidated [ 1, 2].
Chong-Xu Fan   +8 more
openaire   +1 more source

Conus betulinus Transcriptome or Gene expression

2015
The venom of predatory marine cone snails mainly contains a diverse array of unique bioactive peptides commonly referred to as conopeptides or conotoxins. These peptides have proven to be valuable pharmacological probes and potential drugs because of their high specificity and affinity to important ion channels, receptors and transporters of the ...
openaire   +1 more source

TWO-DIMENSIONAL ELECTROPHORESIS ANALYSIS OF CONUS BETULINUS LINNAEUS VENOM PROTEOME AND IDENTIFICATION ON PROTEIN DISULFIDE ISOMERASE

Acta Hydrobiologica Sinica, 2012
Chao PENG   +5 more
exaly   +2 more sources

Exploring Diversity of Conopeptides and Revealing Novel Conoinsulins from Conus betulinus by Proteomic Analyses

Journal of Proteome Research
The venom of cone snails, a potent weapon for predation and defense, contains diverse bioactive peptides (known as conopeptides, or conotoxins) that target various ion channels and receptors, offering potential as pharmacological tools or therapeutics.
Yan Wang   +5 more
openaire   +2 more sources

Preliminary studies on venom of a marine snail Conus betulinus

2005
Ji-Sheng Chen   +9 more
openaire   +1 more source

Novel O-superfamily Conotoxins Identified by cDNA Cloning From Three Vermivorous Conus Species

Chemical Biology and Drug Design, 2006
Dongting Zhangsun   +2 more
exaly  

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