Results 31 to 40 of about 1,273 (215)

Development and implementation of a COVID-19 convalescent plasma program in a middle-income economy

Hematology, Transfusion and Cell Therapy, 2022
Introduction: Convalescent Plasma therapy is one of the therapeutic strategies that has been used for patients with the Covid-19 disease. Implementing a program with national extension to supply hospitals with this blood component is a great challenge ...
Gustavo de Carvalho Duarte, Vivian Simoni, Glaciano Nogueira Ribeiro, Ricardo Haddad, Mariangela Moschen, Rodrigo Spessotto Morais Toledo, Maria Angela Pignata Ottoboni, Alfredo Mendrone-Junior, Dante Mario Langhi   +8 more
doaj   +1 more source

The Role of Disease Severity and Demographics in the Clinical Course of COVID-19 Patients Treated With Convalescent Plasma

Frontiers in Medicine, 2022
Treatment of patients with COVID-19 using convalescent plasma from recently recovered patients has been shown to be safe, but the time course of change in clinical status following plasma transfusion in relation to baseline disease severity has not yet ...
Tengfei Ma, Chad C. Wiggins, Breanna M. Kornatowski, Ra'ed S. Hailat, Andrew J. Clayburn, Winston L. Guo, Patrick W. Johnson, Jonathon W. Senefeld, Stephen A. Klassen, Sarah E. Baker, Katelyn A. Bruno, DeLisa Fairweather, R. Scott Wright, Rickey E. Carter, Chenxi Li, Michael J. Joyner, Nigel S. Paneth, Nigel S. Paneth   +17 more
doaj   +1 more source

Convalescent plasma therapy in patients with COVID‐19 [PDF]

Journal of Clinical Apheresis, 2020
AbstractThere are currently no licensed vaccines or therapeutics for COVID‐19. Anti‐SARS CoV‐2 antibody‐containing plasmas, obtained from the recovered individuals who had confirmed COVID‐19, have been started to be collected using apheresis devices and stored in blood banks in some countries in order to administer to the patients with COVID‐19 for ...
Yiğenoğlu, Tuğçe Nur, Hacıbekiroğlu, Tuba, Berber, İlhami, Dal, Mehmet Sinan, Baştürk, Abdülkadir, Namdaroğlu, Sinem, Korkmaz, Serdal, Ulas, Turgay, Dal, Tuba, Erkurt, Mehmet Ali, Turgut, Burhan, Altuntaş, Fevzi   +11 more
openaire   +3 more sources

SARS-COV-2 Triggers the Development of Class I and Class II HLA Antibodies in Recovered Convalescent Plasma Donors

Intervirology, 2022
Various studies have shown that SARS-CoV-2 is a highly immunogenic virus. It is known that different types of immunogenic viral pathogens could trigger the formation of HLA antibodies.
Ashraf Dada, Khalid Elhassan, Rayan Mohammed Bawayan, Ghadeer Albishi, Lama Hefni, Sawsan Bassi, Turki Sobahy, Edward Cupler, Nabeela AlBaz, Ghassan Wali, Basem Alraddadi, Abeer N. Alshukairi   +11 more
doaj   +1 more source

Effectiveness of Convalescent Plasma Therapy in Treating COVID-19: an Evidence-based Case Report

Acta Medica Indonesiana, 2022
Background: Convalescent plasma is a potentially beneficial, tolerable, and available additional treatment option for COVID-19. This study aims to evaluate whether the administration of convalescent plasma therapy leads to improved clinical outcomes in ...
Mira Yulianti, Christian Johan, Gurmeet Singh, Eric Daniel Tenda, Herikurniawan Herikurniawan, I Putu Eka Krisnha Wijaya   +5 more
doaj   +2 more sources

Convalescent plasma to treat COVID-19 [PDF]

Blood, 2020
In this issue of Blood, Hegerova et al report on a study of 20 hospitalized patients with severe or critical coronavirus disease 2019 (COVID-19) who were transfused with convalescent plasma (CP); the authors suggest a favorable, albeit modest, benefit as compared with 20 matched (ie, nontransfused) controls, particularly when transfusion was undertaken
openaire   +2 more sources

Convalescent Plasma in the Treatment of Severe COVID-19: A Systematic Review and Meta-Analysis

Iranian Journal of Public Health, 2020
Background: COVID-19 is a public health emergency of international concern. Its incidence rates and mortality are very high; however, so far, an effective drug treatment remains unknown.
Xuanguo ZHANG, Li XI, Fang PANG, Yan DU, Qiuzhen YUAN, Minjuan SHI, Jiping LIU, Hui MA, Bo LI   +8 more
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Convalescent Plasma Reduces Mortality and Decreases Hospitalization Stay in Patients with Moderate COVID-19 Pneumonia

Metabolites, 2021
Humans infected with SARS-CoV-2 may develop COVID-19, which manifests across a wide spectrum of clinical severity ranging from mild upper respiratory tract illnesses to diffuse viral pneumonia, causing acute respiratory failure.
Maamoun Basheer, Elias Saad, Dorin Shlezinger, Nimer Assy   +3 more
doaj   +1 more source

Functional Antibodies in COVID-19 Convalescent Plasma [PDF]

, 2021
Abstract In the absence of an effective vaccine or monoclonal therapeutic, transfer of convalescent plasma (CCP) was proposed early in the SARS-CoV-2 pandemic as an easily accessible therapy. However, despite the global excitement around this historically valuable therapeutic approach, results from CCP trials have been mixed and highly ...
Jonathan D. Herman, Chuangqi Wang, Carolin Loos, Hyunah Yoon, Johanna Rivera, M. Eugenia Dieterle, Denise Haslwanter, Rohit K. Jangra, Robert H. Bortz, Katharine J. Bar, Boris Julg, Kartik Chandran, Douglas Lauffenburger, Liise-anne Pirofski, Galit Alter   +14 more
openaire   +2 more sources

The effect of convalescent plasma therapy on the rate of nucleic acid negative conversion in patients with persistent COVID-19 test positivity

Frontiers in Pharmacology
ObjectiveThis study investigates the association between convalescent plasma therapy and the negative conversion rate in patients with persistent COVID-19 test positivity.MethodA retrospective analysis was conducted on patients with severe or mild to ...
Yixuan Wang, Yixuan Wang, Zhe Xu, Xue Xu, Xue Xu, Shuwen Yang, Shuwen Yang, Yuanyuan Li, Hanwen Zhang, Yufeng Zhang, Fu-Sheng Wang, Ying Wang, Jingfeng Bi   +12 more
doaj   +1 more source