Results 41 to 50 of about 1,273 (215)

Determination of the Concentration of IgG against the Spike Receptor-Binding Domain That Predicts the Viral Neutralizing Activity of Convalescent Plasma and Serum against SARS-CoV-2

Biology, 2021
Several hundred millions of people have been diagnosed of coronavirus disease 2019 (COVID-19), causing millions of deaths and a high socioeconomic burden.
Llipsy Santiago, Iratxe Uranga-Murillo, Maykel Arias, Andrés Manuel González-Ramírez, Javier Macías-León, Eduardo Moreo, Sergio Redrado, Ana García-García, Víctor Taleb, Erandi Lira-Navarrete, Ramón Hurtado-Guerrero, Nacho Aguilo, Maria del Mar Encabo-Berzosa, Sandra Hidalgo, Eva M. Galvez, Ariel Ramirez-Labrada, Diego de Miguel, Rafael Benito, Patricia Miranda, Antonio Fernández, José María Domingo, Laura Serrano, Cristina Yuste, Sergio Villanueva-Saz, José Ramón Paño-Pardo, Julián Pardo   +25 more
doaj   +1 more source

Convalescent plasma for COVID-19: Promising, not proven [PDF]

Cleveland Clinic Journal of Medicine, 2020
While promising, convalescent plasma remains experimental and is not proven effective for COVID-19. In addition, many questions remain regarding the accuracy and predictive value of antibody testing of donors and patients, optimal donor selection, optimal timing, and selection of patients most likely to benefit.
Simon R, Mucha, NurJehan, Quraishy
openaire   +2 more sources

The Efficacy of Convalescent Plasma Use in Critically Ill COVID-19 Patients

Medicina, 2021
Background and Objectives: On 24 March 2020, the United States Food and Drug Administration (FDA) announced the approval of convalescent plasma therapy for critically ill patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) as an ...
Livius Tirnea, Felix Bratosin, Iulia Vidican, Bianca Cerbu, Mirela Turaiche, Madalina Timircan, Madalin-Marius Margan, Iosif Marincu   +7 more
doaj   +1 more source

Effects of potent neutralizing antibodies from convalescent plasma in patients hospitalized for severe SARS-CoV-2 infection

Nature Communications, 2021
There are currently no drugs available to treat SARS-CoV-2 infection. A promising alternative treatment for COVID-19 patients is convalescent plasma. Here, Gharbharan et al.
Arvind Gharbharan, Carlijn C. E. Jordans, Corine GeurtsvanKessel, Jan G. den Hollander, Faiz Karim, Femke P. N. Mollema, Janneke E. Stalenhoef – Schukken, Anthonius Dofferhoff, Inge Ludwig, Adrianus Koster, Robert-Jan Hassing, Jeannet C. Bos, Geert R. van Pottelberge, Imro N. Vlasveld, Heidi S. M. Ammerlaan, Elena M. van Leeuwen – Segarceanu, Jelle Miedema, Menno van der Eerden, Thijs J. Schrama, Grigorios Papageorgiou, Peter te Boekhorst, Francis H. Swaneveld, Yvonne M. Mueller, Marco W. J. Schreurs, Jeroen J. A. van Kampen, Barry Rockx, Nisreen M. A. Okba, Peter D. Katsikis, Marion P. G. Koopmans, Bart L. Haagmans, Casper Rokx, Bart J. A. Rijnders   +31 more
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Analysis of anti-SARS-CoV-2 Omicron-neutralizing antibody titers in different vaccinated and unvaccinated convalescent plasma sources

Nature Communications, 2022
Although COVID-19 convalescent plasma is commonly used for the treatment of immunosuppressed patients, this approach has yielded mixed results. Here, the authors present a systematic review of Omicron-neutralization data in convalescent plasma from ...
David J. Sullivan, Massimo Franchini, Michael J. Joyner, Arturo Casadevall, Daniele Focosi   +4 more
doaj   +1 more source

Neutrophil Lymphocyte Ratio (NLR) in COVID-19 Patients Receiving Convalescent Plasma Therapy

Indonesian Journal of Medical Laboratory Science and Technology, 2022
Recently, a new RNA virus from the Coronaviridae family was discovered, known as SARS-Cov-2. This virus causes pneumonia and inflammation in the body.
Desyani Ariza, Andi Maya Kesrianti, Tazya Anggraini Ruslan   +2 more
doaj   +1 more source

Successful recovery of COVID-19-associated recurrent diarrhea and gastrointestinal hemorrhage using convalescent plasma

Military Medical Research, 2020
Background Gastrointestinal symptoms are not rare among coronavirus disease 2019 (COVID-19) patients, but there have been no reports regarding convalescent plasma therapy for the recovery of gastrointestinal problems in COVID-19 patients.
Li-Bo Zhang, Rong-Rong Pang, Qing-Hua Qiao, Zhi-Hua Wang, Xin-Yi Xia, Chang-Jun Wang, Xiao-Li Xu   +6 more
doaj   +1 more source

Apheresis for collection of Ebola convalescent plasma in Liberia [PDF]

Journal of Clinical Apheresis, 2016
AbstractPurposeThis report describes initiation of apheresis capability in Liberia, Africa to support a clinical trial of convalescent plasma therapy for Ebola Virus Disease.MethodsA bloodmobile was outfitted in the United States as a four‐bed apheresis unit with capabilities including pathogen reduction, electronic blood establishment computer system,
Jerry F, Brown, Kathleen, Rowe, Peter, Zacharias, James, van Hasselt, John M, Dye, David A, Wohl, William A, Fischer, Coleen K, Cunningham, Nathan M, Thielman, David L, Hoover   +9 more
openaire   +2 more sources

Challenges in the collection of convalescent plasma for COVID-19 patients at a plasma therapy trial site

Global Journal of Transfusion Medicine, 2020
Background and Objectives: With no proven treatment guidelines for COVID-19, human convalescent plasma is an option and has been under trial worldwide.
Nidhi Bhatnagar, Mamta Shah, Tarak Patel, Dolly Gohel, Hinal Prajapati, Rajvi Vora   +5 more
doaj   +1 more source

HISTORY OF PLASMA THERAPY: A CURRENTLY USED TREATMENT OPTION FOR COVID-19

İstanbul Tıp Fakültesi Dergisi, 2021
The current pandemic provides the most incredible opportunity to develop convalescent plasma therapy into an effective treatment modality for the coronavirus disease 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2 ...
Esra Bilir, Emine Elif Vatanoğlu Lutz, Ayşe Arzu Akalın   +2 more
doaj   +1 more source