Results 51 to 60 of about 4,048 (131)

Macrophage‐derived galectin‐3 contributes to pyroptosis, apoptosis and necroptosis through TLR4/MyD88/NF‐κB/NLRP3 during atherosclerosis

Clinical and Translational Medicine, Volume 16, Issue 3, March 2026.
Pyroptosis, apoptosis and necroptosis of macrophages occur concurrently during atherosclerosis. Galetein‐3 and NLRP3 are highly expressed in atherosclerotic lesions. Galectin‐3 is principally expressed in macrophages within atherosclerotic plaques. Galectin‐3 interacts with NLRP3, activates TLR4/MyD88/NF‐κB/NLRP3 signal axis, and promotes PANoptosis ...
Zihui Yuan, Haitao Li, Bing Xing Ruan, Hongyi Huang, Yiqing Li, Jian Wang   +5 more
wiley   +1 more source

Laser speckle contrast imaging for blood flow monitoring in predicting outcomes after cerebral ischemia-reperfusion injury in mice

BMC Neuroscience, 2022
Background In the treatment of ischemic cerebral stroke (ICS), most conventional treatments, including carotid endarterectomy and carotid artery stenting, may cause cerebral ischemia-reperfusion injury (CIRI).
Lu Yin, Tengfei Yu, Linggang Cheng, Xinyao Liu, Wei Zhang, Hongxia Zhang, Lijuan Du, Wen He   +7 more
doaj   +1 more source

Molecular imprinting for neurology: Materials, applications, and limitations

Ibrain, Volume 12, Issue 1, Page 3-37, Spring 2026.
Molecularly imprinted materials: diagnostic, therapeutic and research applications in neurology. Molecularly imprinted materials offer high specificity and affinity for target molecules in neurological applications. This review highlights their synthesis, characterisation, and use in diagnostics, research and therapeutics.
Xiaohan Ma, Yingqi Ma, Claudia Marino, Alessandro Poma   +3 more
wiley   +1 more source

Review: Discordant findings in color-coded duplex-sonography and magnetic resonance angiography in symptomatic internal carotid artery stenosis: implications for diagnostic work-up and early intervention

Therapeutic Advances in Neurological Disorders, 2010
Background: Magnetic resonance angiography (MRA) is supposed to be the new ’gold standard’ in the diagnosis of atherosclerotic disease of the extracranial arteries.
Jens Eyding, Christos Krogias, Marcus Seemann, Ralf Gold, Achim Mumme   +4 more
doaj   +1 more source

Advances in high‐resolution photoacoustic imaging techniques for cellular visualization

VIEW, Volume 7, Issue 1, February 2026.
Photoacoustic imaging has gained increasing attention for its potential in high‐resolution microscopy, particularly in the context of cellular visualization. This review highlights recent advancements in high‐resolution photoacoustic imaging techniques aimed at visualizing cellular structures, particularly explore key system configurations, imaging ...
Hyunjun Kye, Moon Sung Kang, Dongyoung Jo, Byullee Park, Hee Jeong Jang, Jeesu Kim, Dong‐Wook Han   +6 more
wiley   +1 more source

Systematic Identification and Functional Validation of CASP10 as a DNA‐Damage‐Responsive Driver of Endothelial Pyroptosis in Atherosclerosis

Journal of Cellular and Molecular Medicine, Volume 30, Issue 4, February 2026.
ABSTRACT Atherosclerosis (AS) is a chronic inflammatory disease driven by endothelial dysfunction and plaque instability. The DNA damage response (DDR) has been implicated in endothelial cell fate; its precise role in AS remains unclear. This study aims to identify DDR‐related biomarkers associated with AS and elucidate their mechanisms in endothelial ...
Xiangrong Meng, Kejian Zhang, Yu Xi, Zhuozhong Wang, Xinyu Zhu, Wenjing Zhang   +5 more
wiley   +1 more source

The fat‐heart entanglement and the role of ‘osteopontin mechanics’ in cardiometabolic senescence

European Journal of Clinical Investigation, Volume 56, Issue 1, January 2026.
Abstract Background Residual cardiovascular (CV) risk persists despite therapeutic advances. Obesity is heterogeneous, and visceral adipose tissue (VAT) dysfunction (‘adiposopathy’) complicates risk stratification. Osteopontin (OPN) is a pleiotropic mediator implicated in VAT inflammation, senescence‐associated pathways, atherosclerosis and myocardial ...
Cristina Michelauz, Fabrizio Montecucco, Luca Liberale, Federico Carbone   +3 more
wiley   +1 more source

Retropharyngeal carotid artery stenosis; potential for minimizing operative complications utilizing transcarotid artery stent revascularization

Journal of Vascular Surgery Cases and Innovative Techniques
Retropharyngeal carotid artery occlusive disease presents a formidable challenge for surgeons due to its anatomic location and increased potential for complications.
Hani Shennib, MD, Victor Huerta, DO
doaj   +1 more source

Explainable Machine‐Learning Model to Classify Culprit Calcified Carotid Plaque in Embolic Stroke of Undetermined Source

Journal of Neuroimaging, Volume 36, Issue 1, January/February 2026.
ABSTRACT Background and Purpose Embolic stroke of undetermined source (ESUS) may be associated with carotid artery plaques with <50% stenosis. Plaque vulnerability is multifactorial, possibly related to intraplaque hemorrhage (IPH), lipid‐rich necrotic core, perivascular adipose tissue (PVAT), and calcifications.
Yu Sakai, Jiehyun Kim, Huy Q. Phi, Andrew C. Hu, Pargol Balali, Konstanze V. Guggenberger, John H. Woo, Daniel Bos, Scott E. Kasner, Brett L. Cucchiara, Luca Saba, Zhi Huang, Daniel Haehn, Jae W. Song   +13 more
wiley   +1 more source

Application Value of Machine Learning Diagnosis Model Based on Multimodal Ultrasound in Carotid Plaque Vulnerability

Journal of Cardiac Surgery, Volume 2026, Issue 1, 2026.
Objective To explore the application value of a machine learning diagnosis model based on multimodal ultrasound in assessing carotid plaque vulnerability. Methods A retrospective study was conducted, selecting 100 patients with carotid plaques admitted to our hospital from January 2022 to August 2023.
Jiaojun Yan, Danlin Wen, Hu Chen, Hang Li, Yunhao Luo, Jin Li, Yuefeng Yang, Lin Zhu, Junxuan He, Qian Diao, Lang Qiao, Jeffrey Goldberger   +11 more
wiley   +1 more source