Results 61 to 70 of about 59,449 (283)

Testicular mRNA‐LNP Delivery: A Novel Therapy for Genetic Spermatogenic Disorders

Advanced Science, EarlyView.
In the current study, we developed a novel therapy for genetic spermatogenic disorders. It was revealed that in vivo delivery of mRNA LNP3 could restore spermatogenesis in Msh5D486Y/D486Y and Maps KO mouse models with meiotic arrest. Notably, the offspring without genomic integration was born using ICSI derived from the rescue of Msh5D486Y/D486Y mouse ...
Chenwang Zhang, Nan Liang, Wenbo Li, Shuai Xu, Peng Li, Wanze Ni, Na Li, Sha Han, Ningjing Ou, Haowei Bai, Yuxiang Zhang, Furong Bai, Yifan Sun, Dewei Qian, Xinjie Bu, Erlei Zhi, Ruhui Tian, Yuhua Huang, Jingpeng Zhao, Fujun Zhao, Hao Chen, Zheng Li, Chencheng Yao   +22 more
wiley   +1 more source

Diagnostic accuracy of sonohysterography vs hysteroscopy in benign uterine endocavitary findings [PDF]

, 2015
OBJECTIVE: To compare diagnostic accuracy of sonohysterography vs hysteroscopy in patients with benign uterine endocavitary findings. PATIENTS AND METHODS: This retrospective study evaluated 202 patients submitted to sonohysterography after transvaginal ...
Bianchi, Paola, Caserta, Donatella, Catalano, Angelica, Cozza, Giuliana, DI PROPERZIO, Matilde, Frega, Antonio, Gentile, M, Manzara, F, Marziani, Rosalia, Milazzo, Gn, Schimberni, Mauro, Torcia, Francesco, Zinna, M   +12 more
core  

Thyroid nodules treated with percutaneous radiofrequency thermal ablation: a comparative study [PDF]

, 2012
Percutaneous radiofrequency thermal ablation (RTA) was reported as an effective tool for the management of thyroid nodules (TNs). The aim of this study was to investigate the effects of RTA and to establish whether they were treatment-related by ...
Assanti, A P, Colao, A, Del Prete, M, Faggiano, A, Fonderico, F, Lombardi, G, Macchia, P E, Marciello, F, Marotta, V, Misso, C, Papini, E, Ramundo, V, Spiezia, S   +12 more
core   +1 more source

Magnesium Structure‐Function Integration Platform for Spatiotemporal Multi‐Modality Therapy: Combining Hormonotherapy and Immunotherapy in Prostate Cancer

Advanced Science, EarlyView.
The schematic illustration of the MHSCG platform for spatiotemporal responsive GRb1 release to induce androgen deprivation therapy (ADT) and immunogenic cell death (ICD) multimodal therapy in prostate cancer. Abstract Metal‐based immunotherapy represents a promising strategy for enhancing antitumor efficacy; however, its clinical application is limited
Rui Zan, Qianping Mao, Keyi Wang, Guodong Zou, Shi Yang, Hua Qiu, Xiang Fang, Guiqing Wang, Xinyi Zhou, Jiexia Wen, Shuai Jiang, Ran Huang, Qiuming Peng, Tao Suo   +13 more
wiley   +1 more source

Impact of Liquid-Based Cytology for Detection of Oral Cancer: A Cross-Sectional Study

Journal of Orofacial Sciences
Introduction: Oral cancer and oral potentially malignant disorders require early and accurate detection for timely intervention and management. Cytological techniques, including liquid-based cytology (LBC) and conventional cytology (CC), play a crucial ...
Lavanya Chandra, Nazeema Juwaria, Savitha Sedouramane, Madan Kumar, Pavaskar Chellakkanu, Ranganathan Kannan   +5 more
doaj   +1 more source

Synergistic Mn‐MOF Activation of Pistol Ribozymes for Cancer Immunotherapy

Advanced Science, EarlyView.
A Mn2+‐based metal–organic framework delivers a catalytic Pistol ribozyme for targeted PD‐L1 mRNA cleavage in tumor cells, with the released Mn2+ not only inducing immune activation in immune cells but also increasing the Pistol ribozyme catalytic activity.
Ming Zhao, Shan Qiao, Jie Bai, Jingjing Zhang, Zhiqin Xi, Zhenzhen Li, Xuelin Zhan, Ying Zhang, Xiaotong Yu, Yao Chen, Yijin Liu   +10 more
wiley   +1 more source

Evaluation of the effectiveness of high-risk human papilloma self-sampling test for cervical cancer screening in Bolivia

BMC Infectious Diseases, 2020
Background In Bolivia the incidence and mortality rates of uterine cervix cancer are the highest in America. The main factor contributing to this situation is the difficulty of establishing and maintaining quality prevention programs based on cytology ...
Gustavo Allende, Pedro Surriabre, Neli Ovando, Pamela Calle, Andrea Torrico, Jaime Villarroel, Michel Bossens, Véronique Fontaine, Patricia Rodriguez   +8 more
doaj   +1 more source

Prevalence of human papillomavirus genotypes in women with normal and abnormal cervical cytology in Iran [PDF]

, 2006
Introduction: HPV infection has a prime etiologic role in development and progression of cervical cancer, one of the most frequent forms of cancer among women in developing countries.
Dastan, J., Ensani, F., Ghaffari, S.R., Mohagheghi, M.A., Mollahajian, H., Moradi, A., Mousavi-Jarrahi, A., Ramezanzadeh, F., Sabokbar, T., Yarandi, F.   +9 more
core  

Nanozymes Integrated Biochips Toward Smart Detection System

Advanced Science, EarlyView.
This review systematically outlines the integration of nanozymes, biochips, and artificial intelligence (AI) for intelligent biosensing. It details how their convergence enhances signal amplification, enables portable detection, and improves data interpretation.
Dongyu Chen, Wang Zheng, Zhihui Zhang, Shenping Yu, Xinxin Hang, Han Wu, Xiao‐Wei Xiang, Wei Mu, Yanli Jiao, Zaizai Dong, Lingqian Chang   +10 more
wiley   +1 more source

Comparison of liquid-based cytology with conventional cytology in the evaluation of abdominal masses

Indian Journal of Pathology and Microbiology, 2020
Liquid-based cytology.Utility of liquid-based cytology (LBC) was compared to conventional smear cytology in ultrasound-guided fine-needle aspirates of abdominal masses.This was a prospective comparative study conducted in collaboration with surgery and pediatrics surgery departments of our institute.Thirty patients presenting with evidence of abdominal
Monisha, Choudhury, Archna R, Pahwa
openaire   +2 more sources