Results 31 to 40 of about 2,307,870 (216)
Autophagy in cancer and protein conformational disorders
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
Order Convergence and Topological Convergence [PDF]
In a complete lattice it is possible to define a notion of convergence (for arbitrary nets) known as order convergence (o-convergence) ; for definitions see [l,p.5°]and [3, p. 65]. As a general rule o-convergence is not a topological convergence; i.e., the lattice cannot be topologized so that nets o-converge if and only if they converge with respect ...
openaire +2 more sources
Evolutionary interplay between viruses and R‐loops
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi+4 more
wiley +1 more source
Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi+26 more
wiley +1 more source
Function spaces and contractive extensions in Approach Theory: The role of regularity
Two classical results characterizing regularity of a convergence space in terms of continuous extensions of maps on one hand, and in terms of continuity of limits for the continuous convergence on the other, are extended to convergence-approach spaces ...
Colebunders, Eva+2 more
core +1 more source
Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak+14 more
wiley +1 more source
Real Convergence, Price Level Convergence and Inflation Differentials in Europe [PDF]
This paper provides a comprehensive review of the factors that can cause price levels to diverge and which are at the root of different inflation rates in Europe including the EU-27.
Egert, Balazs
core +2 more sources
On Strong Convergence to Equilibrium for the Boltzmann Equation with Soft Potentials
The paper concerns $L^1$- convergence to equilibrium for weak solutions of the spatially homogeneous Boltzmann Equation for soft potentials $(-4\le ...
B. Wennberg+32 more
core +3 more sources
Convergent multiples of convergent operators
AbstractLet “X≫0” mean that “the bounded linear Hilbert-space operator X is selfadjoint, positive, and invertible”. We discuss the operators A which are known to be convergent (i.e. have spectral radius less than 1) because they all satisfy Stein's condition P−A∗PA≫0 for a fixed P≫0.
openaire +2 more sources
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim+8 more
wiley +1 more source