Results 101 to 110 of about 386,320 (315)
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Convergence Rate Analysis of LION
CoRRThe LION (evoLved sIgn mOmeNtum) optimizer for deep neural network training was found by Google via program search, with the simple sign update yet showing impressive performance in training large scale networks. Although previous studies have investigated its convergence properties, a comprehensive analysis, especially the convergence rate, is still ...
Yiming Dong, Huan Li 0007, Zhouchen Lin
openaire +2 more sources
Feature Learning With a Divergence-Encouraging Autoencoder for Imbalanced Data Classification
IEEE Access, 2018 Imbalanced data exists commonly in machine learning classification applications. Popular classification algorithms are based on the assumption that data in different classes are roughly equally distributed; however, extremely skewed data, with instances ...
Ruisen Luo +7 more
doaj +1 more source
Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Aging and Cancer, EarlyView.This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha +4 more
wiley +1 more source
Theoretical Prospects of the Solutions of Fractional Order Weakly Singular Volterra Integro Differential Equations and their Approximations with Convergence Analysis [PDF]
, 2020 Subrata Rana, Pratibhamoy Das
openalex +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Joint Position Effects on Biceps Femoris and Peroneal Muscle Activation and Ankle Evertor Strength
Physical Therapy KoreaBackground: The peroneus longus (PL) and peroneus brevis (PB) function as the primary muscles of eversion, a movement closely associated with tibial external rotation for ankle mor-tise stability.
Do-eun Lee +3 more
doaj +1 more source
Convergence Order of the Reproducing Kernel Method for Solving Boundary Value Problems
Mathematical Modelling and Analysis, 2016 In this paper, convergence rate of the reproducing kernel method for solving boundary value problems is studied. The equivalence of two reproducing kernel spaces and some results of adjoint operator are proved.
Zhihong Zhao, Yingzhen Lin, Jing Niu
doaj +1 more source