Results 31 to 40 of about 4,196,490 (255)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Convergence and free-will [PDF]

open access: yes, 2008
If our mind is just an algorithm running on a flesh hardware, then it seems that there is no place for the free-will. An algorithm decides everything based on deterministic computations, or on random inputs, but neither inevitability nor pure hazard is ...
Stoica, Ovidiu Cristinel
core  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Difference Gai Sequences of Interval numbers with respect to Orlicz Function

open access: yesActa Scientiarum: Technology
In this article we have introduced some classes generalized difference () Gai sequences of interval numbers with Orlicz functions M. We have studied some algebraic and topological properties of the classes of sequences like, linearity, completeness ...
Achyutananda Baruah, Amar Jyoti Dutta
doaj   +1 more source

Semilocal Convergence Theorem for the Inverse-Free Jarratt Method under New Hölder Conditions

open access: yesThe Scientific World Journal, 2015
Under the new Hölder conditions, we consider the convergence analysis of the inverse-free Jarratt method in Banach space which is used to solve the nonlinear operator equation. We establish a new semilocal convergence theorem for the inverse-free Jarratt
Yueqing Zhao   +5 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

On paranormed type fuzzy I -convergent double multiplier sequences

open access: yesKuwait Journal of Science, 2013
In this article, we introduce the classes of fuzzy real valued double sequences  and  , where   is a multiplier sequence of non-zero real numbers and   is a double sequence of bounded strictly positive numbers.
M. SEN, S. ROY
doaj  

A method with inertial extrapolation step for convex constrained monotone equations

open access: yesJournal of Inequalities and Applications, 2021
In recent times, various algorithms have been incorporated with the inertial extrapolation step to speed up the convergence of the sequence generated by these algorithms.
Abdulkarim Hassan Ibrahim   +3 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Derivative-free iterations in $R^n$ with point-wise operations for solving systems of nonlinear equations

open access: yesDiscrete and Continuous Models and Applied Computational Science
In this paper, we develop a new family of high-order derivative-free iterative methods for solving systems of nonlinear equations. Specifically, we propose four two-step derivative-free schemes with convergence orders four and five, together with twelve ...
Tugal Zhanlav   +3 more
doaj   +1 more source

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