Results 41 to 50 of about 192,329 (259)

Uniform Convergence and the Free Central Limit Theorem [PDF]

open access: yesComplex Analysis and Operator Theory, 2010
We prove results about uniform convergence of densities in the free central limit theorem without assumptions of boundedness on the support.
openaire   +3 more sources

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

open access: yesFEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Is the road to regional integration paved with pollution convergence? [PDF]

open access: yes
This paper evaluates the impact of free trade agreements (FTAs) on carbon dioxide emissions convergence for a cross-section of 182 countries over the period 1980 to 2008, paying particular attention to Mediterranean and European Union countries. In order
Habib Zitouna   +3 more
core  

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

Free and classical entropy over the circle. [PDF]

open access: yes, 2007
Relative entropy with respect to normalized arclength measure on the circle is greater than or equal to the negative logarithmic energy (Voiculescu's negative free entropy) and is greater than or equal to the modified relative free entropy.
Blower, Gordon
core  

Iterative decoding convergence and termination of serially concatenated codes

open access: yes, 2010
In this paper we demonstrate that previously proposed serially concatenated codes only facilitate iterative decoding convergence towards points that are near but not at the top-right hand corner of the EXIT chart, which typically results in an error ...
Hanzo, L., Maunder, R. G.
core   +1 more source

Stabilization of the trial method for the Bernoulli problem in case of prescribed Dirichlet data [PDF]

open access: yes, 2013
We apply the trial method for the solution of Bernoulli’s free boundary problem when the Dirichlet boundary condition is imposed for the solution of the underlying Laplace equation and the free boundary is updated according to the Neumann boundary ...
Giannoula Mitrou   +3 more
core   +1 more source

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