Results 31 to 40 of about 10,023 (272)

Vergence anomalies in a sample of high school students in South Africa

Journal of Optometry, 2016
Aim: To study the prevalence of nearpoint vergence anomalies (convergence insufficiency, convergence excess and fusional vergence dysfunction) and association with gender, age groups, grade level and study site (suburban and rural).
Samuel Otabor Wajuihian, Rekha Hansraj
doaj   +1 more source

Vergence and Accommodative Dysfunctions in Emmetropic and Myopic Chinese Young Adults

Journal of Ophthalmology, 2019
Purpose. To investigate the association between refractive error and common binocular vision and accommodative dysfunctions in Chinese adults and to report the percentage of these disorders in this sample population. Methods.
Martin Ming-Leung Ma, Anna Chwee Hong Yeo, Mitchell Scheiman, Xiang Chen   +3 more
doaj   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Near vision anomalies in Black high school children in Empangeni, South Africa: A pilot study

African Vision and Eye Health, 2014
Background: The ability to read efficiently and comfortably is important in the intellectual development and academic performance of a child. Some children experience difficulties when reading due to symptoms related to near vision anomalies.
Sam O. Wajuihian, Rekha Hansraj
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Convergence Insufficiency, Accommodative Insufficiency, Visual Symptoms, and Astigmatism in Tohono O’odham Students

Journal of Ophthalmology, 2016
Purpose. To determine rate of convergence insufficiency (CI) and accommodative insufficiency (AI) and assess the relation between CI, AI, visual symptoms, and astigmatism in school-age children. Methods.
Amy L. Davis, Erin M. Harvey, J. Daniel Twelker, Joseph M. Miller, Tina Leonard-Green, Irene Campus   +5 more
doaj   +1 more source

Prevalence of different types of intermittent exotropia among exotropic children at Ain Shams University ophthalmology outpatient clinic

Journal of the Egyptian Ophthalmological Society, 2021
Introduction Intermittent exotropia ‘X(T)’ is a disorder of binocular eye movement control, in which one eye intermittently moves outward. It is the commonest type of exodeviation and is usually detected by the parents in early childhood. Patients with X(
Rehab A.M Sallam, Noha M Samak, Ahmed T Ismail, Mohammad A Rashad   +3 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source