Results 111 to 120 of about 14,949,583 (325)
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
Communication-Efficient Zeroth-Order Adaptive Optimization for Federated Learning
MathematicsFederated learning has become a prevalent distributed training paradigm, in which local devices collaboratively train learning models without exchanging local data.
Ping Xie +5 more
doaj +1 more source
A modified subgradient extragradient method for solving monotone variational inequalities
Journal of Inequalities and Applications, 2017 In the setting of Hilbert space, a modified subgradient extragradient method is proposed for solving Lipschitz-continuous and monotone variational inequalities defined on a level set of a convex function.
Songnian He, Tao Wu
doaj +1 more source
On the Positive Effect of Delay on the Rate of Convergence of a Class of Linear Time-Delayed Systems
, 2019 This paper is a comprehensive study of a long observed phenomenon of increase in the stability margin and so the rate of convergence of a class of linear systems due to time delay.
Kia, Solmaz S., Moradian, Hossein
core +1 more source
Convergence, capital accumulation and the nominal exchange rate [PDF]
, 2007 This paper develops a flexible price, two-sector nominal growth model, in order to study the role of the exchange rate regime in capital accumulation (convergence).
Benczur, Peter, Konya, Istvan
core
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
A Note on Averaging Principles for Fractional Stochastic Differential Equations
Fractal and FractionalOver the past few years, many scholars began to study averaging principles for fractional stochastic differential equations since they can provide an approximate analytical method to reduce such systems.
Jiankang Liu +5 more
doaj +1 more source
Convergence of the D-iteration algorithm: convergence rate and asynchronous distributed scheme
, 2013 In this paper, we define the general framework to describe the diffusion operators associated to a positive matrix. We define the equations associated to diffusion operators and present some general properties of their state vectors. We show how this can
Burnside, Gérard +2 more
core +1 more source
Convergence Rates for Branching Processes
The Annals of Probability, 1976 Almost sure estimates of the rate of convergence for the supercritical Galton-Watson process are obtained, e.g. $W - W_n = o(m^{-n/q})$ a.s. if and only if $E(Z_1^p \mid Z_0 = 1) < \infty$, where $1 < p < 2, 1/p + 1/q = 1$. Extensions to the multitype and continuous time cases are outlined.
openaire +3 more sources