Results 91 to 100 of about 6,006,594 (257)

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Heterogeneous Convergence [PDF]

open access: yes
We use U.S. county-level data containing 3,058 cross-sectional observations and 41 conditioning variables to study economic growth and explore possible heterogeneity in growth determination across 32 individual states.
Daniel Levy   +2 more
core  

Tunable Derivative-Matching Expansions

open access: yesMathematics
The usual power series ∑αnxn are generalized by the substitution x→g(x) to power series built from a function ∑angn(x). The key feature of our approach consists in using functions g with free parameters g(x)=g({pi},x); the resulting expansions thus keep ...
Andrej Liptaj
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Hitting and Hoping? Meeting the Exchange Rate and Inflation Criteria during a Period of Nominal Convergence [PDF]

open access: yes
This paper analyses the problem faced by CEECs wishing to join the Euro who must hit both an inflation and exchange rate criterion during a period of nominal convergence.
John Lewis
core  

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Developing Higher-Order Unconditionally Positive Finite Difference Methods for the Advection Diffusion Reaction Equations

open access: yesAxioms
This study introduces the higher-order unconditionally positive finite difference (HUPFD) methods to solve the linear, nonlinear, and system of advection–diffusion–reaction (ADR) equations.
Ndivhuwo Ndou   +2 more
doaj   +1 more source

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