Results 81 to 90 of about 6,006,594 (257)
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
AppliedMathThis study presents a comparative numerical investigation of second-order and fourth-order Runge–Kutta methods for solving chaotic dynamical systems. The Lorenz, Genesio–Tesi, and Rössler systems are considered because of their nonlinear behavior and ...
Ndivhuwo Ndou
doaj +1 more source
An Effective Cuckoo Search Algorithm for Node Localization in Wireless Sensor Network
Sensors, 2016 Localization is an essential requirement in the increasing prevalence of wireless sensor network (WSN) applications. Reducing the computational complexity, communication overhead in WSN localization is of paramount importance in order to prolong the ...
Jing Cheng, Linyuan Xia
doaj +1 more source
Topological network features determine convergence rate of distributed average algorithms. [PDF]
Sci Rep, 2022 Sirocchi C, Bogliolo A.
europepmc +1 more source
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
A rate of convergence in clustering analysis [PDF]
, 1992 We present a result about stochastic boundedness of stable empirical processes on Vapnik-Cervonenkis classes of functions and we apply it to obtain a rate of convergence for the approximation between the sample and the populational variation in the k ...
Romo, Juan
core +1 more source
On the convergence rate of the Kačanov scheme for shear-thinning fluids. [PDF]
Calcolo, 2022 Heid P, Süli E.
europepmc +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Path Planning Optimization of Smart Vehicle With Fast Converging Distance-Dependent PSO Algorithm
IEEE Open Journal of Intelligent Transportation SystemsPath planning is a crucial technology and challenge in various fields, including robotics, autonomous systems, and intelligent transportation systems.
Muhammad Haris, Haewoon Nam
doaj +1 more source