Results 51 to 60 of about 1,380,157 (288)
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
A refinement of estimates of the convergence rate obtained earlier in the multidimensional central limit theorem for the sums of vectors generated by the sequences of random variables with mixing is close to optimal. This has been achieved by imposing an
F.G. Gabbasov +2 more
doaj
A Discrete-Time Fractional-Order Flocking Control Algorithm of Multi-Agent Systems
In this paper, a discrete-time fractional flocking control algorithm of multi-agent systems is put forward to address the slow convergence issue of multi-agent systems. Firstly, by introducing Grünwald-Letnikov (G-L) fractional derivatives, the algorithm
Haotian Chen +4 more
doaj +1 more source
Convergence rate of Krasulina estimator [PDF]
Principal component analysis (PCA) is one of the most commonly used statistical procedures with a wide range of applications. Consider the points $X_1, X_2,..., X_n$ are vectors drawn i.i.d. from a distribution with mean zero and covariance $ $, where $ $ is unknown. Let $A_n = X_nX_n^T$, then $E[A_n] = $. This paper consider the problem of finding
openaire +3 more sources
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Interest Rate Convergence in Bangladesh
Financial liberalization, a widely-accepted policy paradigm since the 1980s, aims to remove financial repression and thus establish an efficient financial sector as a pre-requisite for financial development.
Dewan M. Rahman, Kohinur Akter
doaj
On the Convergence Rate of the Caputo Fractional Difference Logistic Map of Nilpotent Matrices
The convergence rate of the Caputo fractional difference logistic map of nilpotent matrices is investigated in this paper. The divergence rate of the auxiliary parameters governing the dynamics of nilpotents is exponential and is multiple to the Lyapunov
Rasa Smidtaite +3 more
doaj +1 more source
The convergence rate for the laws of logarithms under sub-linear expectations
Let $ \{X_n; n\geq1\} $ be a sequence of independent and identically distributed random variables in a sub-linear expectation space $ (\Omega, \mathcal{H}, \hat{\mathbb{E}}) $.
Qunying Wu
doaj +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Procedure for finding estimate of convergence rate
Here is presented one method for finding convergence rate estimate of probability function.
Robertas Vilkas, Algimantas Aksomaitis
doaj +3 more sources

