Results 51 to 60 of about 6,006,594 (257)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Rate of convergence of Wong-Zakai approximations for SDEs and SPDEs [PDF]
, 2005 In the work we estimate the rate of convergence of the Wong-Zakai type of approximations for SDEs and SPDEs. Two cases are studied: SDEs in finite dimensional settings and evolution stochastic systems (SDEs in the infinite dimensional case).
Shmatkov, Anton
core
Monetary convergence and risk premiums in the EU candidate countries [PDF]
This study examines the link between various monetary policy regimes and the ability to manage inflation and exchange rate risk premiums in the EU candidate countries as they undergo monetary convergence to the eurozone. The underlying hypothesis is that
Orlowski, Lucjan T.
core +2 more sources
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Convergence Rate Analysis of MAP Coordinate Minimization Algorithms
, 2019 Finding maximum a posteriori (MAP) assignments in graphical models is an important task in many applications. Since the problem is generally hard, linear programming (LP) relaxations are often used.
Meshi, Ofer +2 more
core
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Exchange Rate Risk and Convergence to the Euro [PDF]
This paper proposes a new monetary policy framework for effectively navigating the path to adopting the euro. The proposed policy is based on relative inflation forecast targeting and incorporates an ancillary target of declining exchange rate risk ...
Lucjan T Orlowski
core
Convergence and rate optimality of adaptive multilevel stochastic Galerkin FEM [PDF]
, 2022 We analyze an adaptive algorithm for the numerical solution of parametric elliptic partial differential equations in two-dimensional physical domains, with coefficients and right-hand-side functions depending on infinitely many (stochastic) parameters ...
Bespalov, Alex +2 more
core +1 more source
Communication-Efficient Zeroth-Order Adaptive Optimization for Federated Learning
MathematicsFederated learning has become a prevalent distributed training paradigm, in which local devices collaboratively train learning models without exchanging local data.
Ping Xie +5 more
doaj +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source