Results 61 to 70 of about 2,453,874 (341)
FEBS Letters, EarlyView.Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma +8 more
wiley +1 more source
Convergence of Conditional Entropy for Long Range Dependent Markov Chains [PDF]
arXiv, 2021 In this paper we consider the convergence of the conditional entropy to the entropy rate for Markov chains. Convergence of certain statistics of long range dependent processes, such as the sample mean, is slow. It has been shown in Carpio and Daley \cite{carpio2007long} that the convergence of the $n$-step transition probabilities to the stationary ...
arxiv
, 2010 In this paper, we study the convergence behavior of distributed iterative algorithms with quantized message passing. We first introduce general iterative function evaluation algorithms for solving fixed point problems distributively.
Cui, Ying, Lau, Vincent K. N.
core +1 more source
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
On Almost Sure Convergence Rates of Stochastic Gradient Methods [PDF]
arXiv, 2022 The vast majority of convergence rates analysis for stochastic gradient methods in the literature focus on convergence in expectation, whereas trajectory-wise almost sure convergence is clearly important to ensure that any instantiation of the stochastic algorithms would converge with probability one.
arxiv
Convergence time for unbiased quantized consensus [PDF]
52nd IEEE Conference on Decision and Control, 2013 We revisit the quantized consensus problem on undirected connected graphs, and obtain some strong results on expected time to convergence. This is unbiased consensus, because the edges emanating from a node have equal probability of being selected. The paper first develops an approach that bounds the expected convergence time of the underlying discrete-
Etesami, Seyed Rasoul, Basar, Tamer
openaire +2 more sources
miRNA‐29 regulates epidermal and mesenchymal functions in skin repair
FEBS Letters, EarlyView.miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan +10 more
wiley +1 more source
Creep Characterization of Inconel 718 Lattice Metamaterials Manufactured by Laser Powder Bed Fusion
Advanced Engineering Materials, EarlyView., 2023 Herein, the creep characteristics of additively manufactured Inconel 718 metamaterials are investigated. The creep behavior of metamaterials and the effects of microstructural defects are assessed, and the microstructure defects are accurately captured using Kachanov's creep damage model.
Akash Singh Bhuwal +5 more
wiley +1 more source
Evolutionary interplay between viruses and R‐loops
FEBS Letters, EarlyView.Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi +4 more
wiley +1 more source
Advanced Engineering Materials, EarlyView., 2023 This study aims to explore the feasibility of using a structure inspired by the features of horsetail and human spine as the potential helmet liner, targeting at mitigation of acceleration‐induced injuries. A parametric study is conducted to investigate the effect of individual geometrical variables in the design, indicating its capability to reduce ...
Bing Leng +3 more
wiley +1 more source