Results 101 to 110 of about 3,143,654 (302)

Host and venom evolution in parasitoid wasps: does independently adapting to the same host shape the evolution of the venom gland transcriptome?

BMC Biology
Background Venoms have repeatedly evolved over 100 occasions throughout the animal tree of life, making them excellent systems for exploring convergent evolutionary novelty.
Yi Yang, Shan Xiao, Xianxin Zhao, Yu H. Sun, Qi Fang, Longjiang Fan, Gongyin Ye, Xinhai Ye   +7 more
doaj   +1 more source

Massive Tandem Proliferation of ELIPs Supports Convergent Evolution of Desiccation Tolerance across Land Plants1[OPEN]

Plant Physiology, 2019
A recurrent gene duplication event is found in all surveyed resurrection plant genomes supporting convergent evolution of this trait. Desiccation tolerance was a critical adaptation for the colonization of land by early nonvascular plants.
R. VanBuren, Jeremy D Pardo, Ching Man Wai, Sterling Evans, D. Bartels   +4 more
semanticscholar   +1 more source

Genomic Analysis Revealed a Convergent Evolution of LINE-1 in Coat Color: A Case Study in Water Buffaloes (Bubalus bubalis)

Molecular biology and evolution, 2020
Visible pigmentation phenotypes can be used to explore the regulation of gene expression and the evolution of coat color patterns in animals. Here, we performed whole-genome and RNA sequencing and applied genome-wide association study, comparative ...
Dong Liang, Pengju Zhao, J. Si, L. Fang, E. Pairo-Castineira, Xiaoxiang Hu, Qing Xu, Yali Hou, Yu Gong, Z. Liang, Bingyu Tian, H. Mao, Marnoch Yindee, M. Faruque, Siton Kongvongxay, Souksamlane Khamphoumee, G. Liu, Dong-Dong Wu, J. F. Barker, Jianlin Han, Yi Zhang   +20 more
semanticscholar   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Convergent evolution of germ granule nucleators: A hypothesis

Stem Cell Research, 2017
Germ cells have been considered “the ultimate stem cell” because they alone, during normal development of sexually reproducing organisms, are able to give rise to all organismal cell types.
Arpita Kulkarni, Cassandra G. Extavour
doaj   +1 more source

A GWAS in Latin Americans highlights the convergent evolution of lighter skin pigmentation in Eurasia

Nature Communications, 2019
We report a genome-wide association scan in >6,000 Latin Americans for pigmentation of skin and eyes. We found eighteen signals of association at twelve genomic regions.
K. Adhikari, J. Mendoza-Revilla, A. Sohail, M. Fuentes-Guajardo, Jodie Lampert, J. Chacón-Duque, M. Hurtado, V. Villegas, V. Granja, V. Acuña-Alonzo, C. Jaramillo, W. Arias, R. B. Lozano, Paola Everardo, J. Gómez-Valdés, H. Villamil-Ramírez, C. C. Silva de Cerqueira, Tábita Hunemeier, V. Ramallo, L. Schuler‐Faccini, F. Salzano, R. González‐José, M. Bortolini, S. Canizales-Quinteros, C. Gallo, G. Poletti, G. Bedoya, F. Rothhammer, D. Tobin, Matteo Fumagalli, D. Balding, A. Ruiz-Linares   +31 more
semanticscholar   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Convergent evolution of semiochemicals across Kingdoms: bark beetles and their fungal symbionts

The ISME Journal, 2019
Convergent evolution of semiochemical use in organisms from different Kingdoms is a rarely described phenomenon. Tree-killing bark beetles vector numerous symbiotic blue-stain fungi that help the beetles colonize healthy trees. Here we show for the first
Ting Zhao, Ting Zhao, Ting Zhao, S. Ganji, Christian Schiebe, B. Bohman, B. Bohman, P. Weinstein, P. Krokene, A. Borg-Karlson, C. Unelius   +10 more
semanticscholar   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source