Results 81 to 90 of about 3,143,654 (302)

Convergent evolution in primates and an insectivore [PDF]

Genomics, 2004
The cardiovascular risk factor LPA has a puzzling distribution among mammals, its presence being limited to a subset of primates and a member of the insectivore lineage, the hedgehog. To explore the evolutionary history of LPA, we performed extensive genomic sequence comparisons of multiple species with and without an LPA gene product, such as human ...
Boffelli, Dario, Cheng, Jan-Fang, Rubin, Edward M.   +2 more
openaire   +3 more sources

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Recurrent convergent evolution at amino acid residue 261 in fish rhodopsin

Proceedings of the National Academy of Sciences of the United States of America, 2019
Significance Fish occupy a wide range of light environments that vary depending on the wavelengths absorbed by the local environment, including brackish and freshwater environments in which dissolved organic matter produces a red-shifted visual ...
Jason Hill, Erik D. Enbody, Mats E. Pettersson, C. G. Sprehn, D. Bekkevold, A. Folkvord, L. Laikre, G. Kleinau, P. Scheerer, Leif Andersson, Leif Andersson, Leif Andersson   +11 more
semanticscholar   +1 more source

Convergent evolution with combinatorial peptides [PDF]

FEBS Letters, 2000
Once the sequence of a genome is in hand, understanding the function of its encoded proteins becomes a task of paramount importance. Much like the biochemists who first outlined different biochemical pathways, many genomic scientists are engaged in determining which proteins interact with which proteins, thereby establishing a protein interaction ...
Kay, Brian K, Kasanov, Jeremy, Knight, Stephen, Kurakin, Alexei   +3 more
openaire   +2 more sources

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Convergent evolution of noncoding elements associated with short tarsus length in birds

BMC Biology
Background Convergent evolution is the independent evolution of similar traits in unrelated lineages across the Tree of Life. Various genomic signatures can help identify cases of convergent evolution at the molecular level, including changes in ...
Subir B. Shakya, Scott V. Edwards, Timothy B. Sackton   +2 more
doaj   +1 more source

Robust time estimation reconciles views of the antiquity of placental mammals.

PLoS ONE, 2007
BACKGROUND:Molecular studies have reported divergence times of modern placental orders long before the Cretaceous-Tertiary boundary and far older than paleontological data.
Yasuhiro Kitazoe, Hirohisa Kishino, Peter J Waddell, Noriaki Nakajima, Takahisa Okabayashi, Teruaki Watabe, Yoshiyasu Okuhara   +6 more
doaj   +1 more source

Phenotypic landscape inference reveals multiple evolutionary paths to C4 photosynthesis

eLife, 2013
C4 photosynthesis has independently evolved from the ancestral C3 pathway in at least 60 plant lineages, but, as with other complex traits, how it evolved is unclear.
Ben P Williams, Iain G Johnston, Sarah Covshoff, Julian M Hibberd   +3 more
doaj   +1 more source

Convergent Evolution of Mucosal Immune Responses at the Buccal Cavity of Teleost Fish

iScience, 2019
Summary The buccal mucosa (BM) is a critical first line of defense in terrestrial animals. To gain further insights into the evolutionary origins and primordial roles of BM in teleosts here we show that rainbow trout, a teleost fish, contains a diffuse ...
Yong-yao Yu, Yong-yao Yu, Wei-guang Kong, Hao-yue Xu, Zhen-yu Huang, Xiaoting Zhang, L. Ding, Shuai Dong, Guang-mei Yin, Fen Dong, Wei Yu, Jia-feng Cao, Kai-feng Meng, Xia Liu, Yu Fu, Xuezhen Zhang, Yong‐An Zhang, J. Sunyer, Zhen Xu   +18 more
semanticscholar   +1 more source

Molecular adaptation and convergent evolution of frugivory in Old World and neotropical fruit bats

Molecular Ecology, 2020
Although cases of independent adaptation to the same dietary niche have been documented in mammalian ecology, the molecular correlates of such shifts are seldom known.
Kai Wang, S. Tian, J. Galindo‐González, L. Dávalos, Yuzhi Zhang, Huabin Zhao   +5 more
semanticscholar   +1 more source