Results 91 to 100 of about 2,062,237 (252)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Impact of ohmic heating on MHD mixed convection flow of Casson fluid by considering Cross diffusion effect

Nonlinear Engineering, 2019
Present communication aims to discuss the impact of viscous dissipation on MHD flow, heat and mass transfer of Casson fluid over a plate by considering mixed convection.
Gireesha B.J., Ganesh Kumar K., Krishnamurthy M.R., Manjunatha S., Rudraswamy N.G.   +4 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Procedure-related baseline characteristics.

, 2018
Procedure-related baseline characteristics.
Dong Seop Jeong (5832767), Jin Kyung Hwang (2938212), Hye Bin Gwag (3636730), Keumhee Carriere (5832770), Kyoung-min Park (2817493), Joonghyun Ahn (3636724), Young Keun On (2817502), Seung-Jung Park (95648), June Soo Kim (2817487)   +8 more
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Reliability and factorial validity of the Persian Adult ADHD Self-Report scale in university students

Revista Portuguesa de Investigação Comportamental e Social
Background and Aim: Adult attention-deficit/hyperactivity disorder (ADHD) is prevalent and impairing, yet underdiagnosed in many low- and middle-income countries, partly due to the scarcity of culturally adapted screening tools.
Zahra Shahnavaz, Mohammad Bagher Hassanvand   +1 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Cultural adaptation and psychometric validation of the Caring Efficacy scale in a sample of Italian nurses.

PLoS ONE, 2019
Caring is the essence of nursing practice. Caring Efficacy scale was developed with the purpose of measuring nurses' perceived self-efficacy in orienting and maintaining caring relationships with patients.
Cesar Ivan Aviles Gonzalez, Maura Galletta, Paola Melis, Paolo Contu, Jean Watson, Gabriele Finco, Maria Francisca Jimenez Herrera   +6 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Linear Amine-Linked Oligo-BODIPYs: Convergent Access via Buchwald-Hartwig Coupling [PDF]

A convergent route towards nitrogen-bridged BODIPY oligomers has been developed. The synthetic key step is a Buchwald-Hartwig cross-coupling reaction of an alpha-amino-BODIPY and the respective halide.
Sebastian H., Röttger, Lukas J., Patalag, Peter G., Jones, Daniel B., Werz, Lukas, Milbrandt, Felix, Hasenmaile, Burkhard, Butschke   +6 more
core   +2 more sources